UniProt Accession

 D3Z367_MOUSE; D3Z367 

Genbank Protein ID

 CT954323 

Genbank Nucleotide ID

  

Protein Name

 Protein Gm2046 

Protein Synonyms/Alias

  

Gene Name

 Gm2046 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
104	PDEARSLKAYGELPE	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Initiation factor; Protein biosynthesis; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 144 AA 

Protein Sequence

Gene Ontology

 GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. 

Interpro

 IPR012340; NA-bd_OB-fold.
 IPR006196; RNA-binding_domain_S1_IF1.
 IPR001253; TIF_eIF-1A.
 IPR018104; TIF_eIF-1A_CS. 

Pfam

 PF01176; eIF-1a 

SMART

 SM00652; eIF1a 

PROSITE

 PS01262; IF1A
 PS50832; S1_IF1_TYPE 

PRINTS