CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031432
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ53944, highly similar to Eukaryotic translation initiation factor 4 gamma 3 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
391KFIGELFKLKMLTEAubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Initiation factor; Protein biosynthesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1075 AA 
Protein Sequence
MSQGFHPERD PSDLKKVKAV EENGEEAEPV RNGAESVSEG EGIDANSGST DSSGDGVTFP 60
FKPESWKPTD TEGKKQYDRE FLLDVQFMPA CIQKPEGLPP ISDVVLDKIN QPKLPMRTLD 120
PRILPRGPDF TPAFADFGRQ TPGGRGIPIC KVQSRHGLPI LEQSKAPTCP PLVMSHPPMK 180
SLPLGLLDVG SRRSQPGQRR EPRKIITVSV KEDVHLKKAE NAWKPSQKRD SQADDPENIK 240
TQELFRKVRS ILNKLTPQMF NQLMKQVSGL TVDTEERLKG VIDLVFEKAI DEPSFSVAYA 300
NMCRCLVTLK VPMADKPGNT VNFRKLLLNR CQKEFEKDKA DDDVFEKKQK ELEAASAPEE 360
RTRLHDELEE AKDKARRRSI GNIKFIGELF KLKMLTEAIM HDCVVKLLKN HDEESLECLC 420
RLLTTIGKDL DFEKAKPRMD QYFNQMEKIV KERKTSSRIR FMLQDVIDLR LCNWVSRRAD 480
QGPKTIEQIH KEAKIEEQEE QRKVQQLMTK EKRRPGVQRV DEGGWNTVQG AKNSRVLDPS 540
KFLKITKPTI DEKIQLVPKA QLGSWGKGSS GGAKASETDA LRSSASSLNR FSALQPPAPS 600
GSTPSTPVEF DSRRTLTSRG SMGREKNDKP LPSATARPNT FMRGGSSKDL LDNQSQEEQR 660
REMLETVKQL TGGVDVERNS TEAERNKTRE SAKPEISAMS AHDKAALSEE ELERKSKSII 720
DEFLHINDFK EAMQCVEELN AQGLLHVFVR VGVESTLERS QITRDHMGQL LYQLVQSEKL 780
SKQDFFKGFS ETLELADDMA IDIPHIWLYL AELVTPMLKE GGISMRELTI EFSKPLLPVG 840
RAGVLLSEIL HLLCKQMSHK KVGALWREAD LSWKDFLPEG EDVHNFLLEQ KLDFIESDSP 900
CSSEALSKKE LSAEELYKRL EKLIIEDKAN DEQIFDWVEA NLDEIQMSSP TFLRALMTAV 960
CKAAIIADSS TFRVDTAVIK QRVPILLKYL DSDTEKELQA LYALQASIVK LDQPANLLRM 1020
FFDCLYDEEV ISEDAFYKWE SSKDPAEQNG KGVALKSVTA FFTWLREAEE ESEDN 1075 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
 GO:0016070; P:RNA metabolic process; IEA:InterPro. 
Interpro
 IPR016024; ARM-type_fold.
 IPR003891; Initiation_fac_eIF4g_MI.
 IPR016021; MIF4-like_typ_1/2/3.
 IPR003890; MIF4G-like_typ-3.
 IPR003307; W2_domain. 
Pfam
 PF02847; MA3
 PF02854; MIF4G
 PF02020; W2 
SMART
 SM00515; eIF5C
 SM00544; MA3
 SM00543; MIF4G 
PROSITE
 PS51366; MI
 PS51363; W2 
PRINTS