CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011260
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Reticulon-like protein 1 
Protein Synonyms/Alias
  
Gene Name
 RTN1 
Gene Synonyms/Alias
 YDR233C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
125TVFAQVPKHTFKTAVacetylation[1]
185GVEISKQKTQEFSQMubiquitination[2]
203KTKPYLDKVESKLGPacetylation[1]
218ISNLVKSKTAPVSSTubiquitination[2]
235PQTASTSKLAADVPLubiquitination[2]
284NELKKSTKNLQNELEubiquitination[2]
292NLQNELEKNNA****ubiquitination[2, 3]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [3] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047
Functional Description
  
Sequence Annotation
 DOMAIN 20 220 Reticulon.
 MOD_RES 186 186 Phosphothreonine.
 MOD_RES 219 219 Phosphothreonine.
 MOD_RES 232 232 Phosphoserine.  
Keyword
 Coiled coil; Complete proteome; Direct protein sequencing; Endoplasmic reticulum; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 295 AA 
Protein Sequence
MSASAQHSQA QQQQQQKSCN CDLLLWRNPV QTGKYFGGSL LALLILKKVN LITFFLKVAY 60
TILFTTGSIE FVSKLFLGQG LITKYGPKEC PNIAGFIKPH IDEALKQLPV FQAHIRKTVF 120
AQVPKHTFKT AVALFLLHKF FSWFSIWTIV FVADIFTFTL PVIYHSYKHE IDATVAQGVE 180
ISKQKTQEFS QMACEKTKPY LDKVESKLGP ISNLVKSKTA PVSSTAGPQT ASTSKLAADV 240
PLEPESKAYT SSAQVMPEVP QHEPSTTQEF NVDELSNELK KSTKNLQNEL EKNNA 295 
Gene Ontology
 GO:0032541; C:cortical endoplasmic reticulum; IDA:SGD.
 GO:0005794; C:Golgi apparatus; IDA:SGD.
 GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; IDA:UniProtKB.
 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0071788; P:endoplasmic reticulum tubular network maintenance; IGI:SGD.
 GO:0051292; P:nuclear pore complex assembly; IGI:SGD. 
Interpro
 IPR003388; Reticulon. 
Pfam
 PF02453; Reticulon 
SMART
  
PROSITE
 PS50845; RETICULON 
PRINTS