| Tag | Content |
|---|
| CPLM ID | CPLM-023937 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Sorting nexin-14 |
Protein Synonyms/Alias | |
Gene Name | SNX14 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 148 | DIPSIITKKLLKAAM | ubiquitination | [1] | | 169 | VKARQKVKNTEFLQQ | ubiquitination | [1] | | 277 | PLVPFLQKFAEPRNK | ubiquitination | [1] | | 710 | KLFNDLFKNNANRAE | ubiquitination | [1] | | 820 | QDKQKGAKQTFEEMM | ubiquitination | [1] | | 884 | PELNKVQKEVTSVTS | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | May be involved in several stages of intracellular trafficking (By similarity). |
Sequence Annotation | DOMAIN 130 304 PXA.
DOMAIN 336 468 RGS.
DOMAIN 570 690 PX.
CROSSLNK 196 196 Glycyl lysine isopeptide (Lys-Gly) |
Keyword | 3D-structure; Alternative splicing; Complete proteome; Isopeptide bond; Membrane; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport; Ubl conjugation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 946 AA |
Protein Sequence | MVPWVRTMGQ KLKQRLRLDV GREICRQYPL FCFLLLCLSA ASLLLNRYIH ILMIFWSFVA 60
GVVTFYCSLG PDSLLPNIFF TIKYKPKQLG LQELFPQGHS CAVCGKVKCK RHRPSLLLEN 120
YQPWLDLKIS SKVDASLSEV DIPSIITKKL LKAAMKHIEV IVKARQKVKN TEFLQQAALE 180
EYGPELHVAL RSRRDELHYL RKLTELLFPY ILPPKATDCR SLTLLIREIL SGSVFLPSLD 240
FLADPDTVNH LLIIFIDDSP PEKATEPASP LVPFLQKFAE PRNKKPSVLK LELKQIREQQ 300
DLLFRFMNFL KQEGAVHVLQ FCLTVEEFND RILRPELSND EMLSLHEELQ KIYKTYCLDE 360
SIDKIRFDPF IVEEIQRIAE GPYIDVVKLQ TMRCLFEAYE HVLSLLENVF TPMFCHSDEY 420
FRQLLRGAES PTRNSKLNRN TQKRGESFGI SRIGSKIKGV FKSTTMEGAM LPNYGVAEGE 480
DDFIEEGIVV MEDDSPVEAV STPNTPRNLA AWKISIPYVD FFEDPSSERK EKKERIPVFC 540
IDVERNDRRA VGHEPEHWSV YRRYLEFYVL ESKLTEFHGA FPDAQLPSKR IIGPKNYEFL 600
KSKREEFQEY LQKLLQHPEL SNSQLLADFL SPNGGETQFL DKILPDVNLG KIIKSVPGKL 660
MKEKGQHLEP FIMNFINSCE SPKPKPSRPE LTILSPTSEN NKKLFNDLFK NNANRAENTE 720
RKQNQNYFME VMTVEGVYDY LMYVGRVVFQ VPDWLHHLLM GTRILFKNTL EMYTDYYLQC 780
KLEQLFQEHR LVSLITLLRD AIFCENTEPR SLQDKQKGAK QTFEEMMNYI PDLLVKCIGE 840
ETKYESIRLL FDGLQQPVLN KQLTYVLLDI VIQELFPELN KVQKEVTSVT SWM 893 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. GO:0007154; P:cell communication; IEA:InterPro. GO:0015031; P:protein transport; IEA:UniProtKB-KW. GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |