CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014950
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Keratin, type I cytoskeletal 42 
Protein Synonyms/Alias
 Cytokeratin-42; CK-42; Keratin-17n; Keratin-42; K42; Type I keratin Ka22 
Gene Name
 Krt42 
Gene Synonyms/Alias
 Ka22 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
222EMQIESLKEELAYLRacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 REGION 4 93 Head.
 REGION 94 401 Rod.
 REGION 94 129 Coil 1A.
 REGION 130 147 Linker 1.
 REGION 148 239 Coil 1B.
 REGION 240 262 Linker 12.
 REGION 263 401 Coil 2.
 REGION 402 452 Tail.  
Keyword
 Coiled coil; Complete proteome; Cytoplasm; Direct protein sequencing; Intermediate filament; Keratin; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 452 AA 
Protein Sequence
MASTTSVRQF STSGSVKGLC APGMGFSRMS SVRVGGACRA PSLLGGGSCG NMSVTSSRFS 60
AGLGGGYGGG YTCSLGGGFG SSFGVSDALL GGSEKETMQN LNDRLATYLD RVRALEEANA 120
DLEVKIREWY KKQGPGPARD YSPYFKTIED LRNKILAATI DNASIVLQID NARLAADDFR 180
TKYETELNLR MSVEADINGL RRVLDELTLA RADLEMQIES LKEELAYLRK NHEEEMNALR 240
GQVGGDVNVE MDAAPGVDLS RILNEMRDQY EKMAEKNRKD AEEWFFTKTE ELNREVATNT 300
EALQSSRTEI TELRRSVQNL EIELQSQLSM KASLENSLAE TEARYGAQLA QLQGLISSVE 360
QQLCELRCDM ERQNHEYQVL LDVKTRLEQE IATYRRLLEG EDAHLATQYS SSLASQPSRE 420
GMVTSRQVRT IVEEVQDGKV VSSREQVHRS TH 452 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
 GO:0005198; F:structural molecule activity; IEA:InterPro. 
Interpro
 IPR016044; F.
 IPR001664; IF.
 IPR018039; Intermediate_filament_CS.
 IPR002957; Keratin_I.
 IPR009053; Prefoldin. 
Pfam
 PF00038; Filament 
SMART
  
PROSITE
 PS00226; IF 
PRINTS
 PR01248; TYPE1KERATIN.