CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030001
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MCG56945 
Protein Synonyms/Alias
 Protein Gm382 
Gene Name
 Gm382 
Gene Synonyms/Alias
 mCG_56945 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
416EKFDIIVKDLMSKMEacetylation[1, 2, 3]
416EKFDIIVKDLMSKMEsuccinylation[2]
416EKFDIIVKDLMSKMEubiquitination[4]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [4] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1250 AA 
Protein Sequence
MNSKRNSASQ QNKSAQKENH YKNPNDVVRM SRNDKEVNQH LEQGNFSGNP EETAESSNSN 60
IFKAGEISNL TRIFHVLLEE EKYLTQFGEG TLAKFYAHIM ENTGVNLESS FVKDQGLYVT 120
VFGNPEAVTN AENEIFKWCQ KQYLPLTLIS KQEHCFFLNQ TGNKSQDLEQ EGQINTQITS 180
PHNQNNSINS VDVNQTKMKS SDGSLSTSAR SNKGDIQILE MEKSFNPLTV KPYLQASDIF 240
QETEEHVPFE LSSAKETDLD INEGQLHVDQ IGCLKNDMIK KTSTITEGMM MTFQDSGTRS 300
LKRHFLEEIL DTSEDSTGQS QSESISDYMT QHSDLDSSGE LFNEADDNDD DYIASSIFAP 360
SWLHRFIIGT KGEEISEITE CVPKVQIHFT AKDKITLKGP IDDVNYAQEK FDIIVKDLMS 420
KMEYTEINSD SKFYKYLTGN NGEILNRITE KNQVSITMFP ENESNYSIRI EGESLGVHQA 480
KKELLDLANN LEEEYSQDII IKHQFHHILI GQKGERVREI CKKFPDVILN FPHPAEKSDI 540
VQLIGPRYES EKCAQYLENM LTDIKENNYS ISVPIIKKLH KRIIGKGVSN IRKISEATNT 600
KITFPPESCN SEEFIITGYP ENCEIARNWI LSLQQELADT AEEEIIIPAN LYKHLTNPKE 660
CLLNSIIEEC GKIHLHFPKG KSNLNKIIIM GTIENVEKAK TKLLKLSEEE QAKNYSETLH 720
IKSKYHQFLL NKNGGNISKI CDETGTCVFF PNPTNKDQET ITITGTEESV KEVQKQLDDL 780
VKDFENEVDD SILINRRFHH YFVMRRGQLL KEMAEDYGGV VITFSYSGRQ NTKVTIRGAK 840
PCVEAAKKHI KEIFEPLGSQ ITTRYVLPHS FQPFIMGPIS SRIQQIARDY KVEIKFPDIE 900
KPALNMDLGT HEKGKEKWKR TAKEIAPNSP RKGDTIFISG QVENCKAATE ALASIIPVTT 960
EVHVPLHLQP YIIGHKGSGL RKLVKEYEVH MQVSQPGKNS DIISIMGLSA NVEQAKIKLQ 1020
KRVKSLQMEV EDRTLRNFKL MFNLDPKYQA KITGHKGLLI TQICTEHDVT IHFPKKGTHD 1080
MQEQITITGY KENTLAARDA IMRLLHKIEK TISKEITLNQ QVRGNVIGVR GKTINKIMDQ 1140
YQVDIRLPPK GLYNPNITVT GLADNVEKAI EHILNLEKYY LSAAINHGSQ QEQPKSMSLC 1200
NIAMTPSKSF VRKYVPCYAK TTTKLPDVDN CEHFPRLKQR TSSKTHPSKL 1250 
Gene Ontology
 GO:0003723; F:RNA binding; IEA:InterPro. 
Interpro
 IPR004087; KH_dom.
 IPR004088; KH_dom_type_1. 
Pfam
 PF00013; KH_1
 PF13014; KH_3 
SMART
 SM00322; KH 
PROSITE
 PS50084; KH_TYPE_1 
PRINTS