CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029097
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Probable ATP-dependent DNA helicase HFM1 
Protein Synonyms/Alias
  
Gene Name
 HFM1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
768VGLDIQQKLTVFYLEubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1114 AA 
Protein Sequence
MEVPLPWLNI KIVYMAPIKA LCSQRFDDWK EKFGPIGLNC KELTGDTVMD DLFEIQHAHI 60
IMTTPEKWDS MTRKWRDNSL VQLVRLFLID EVHIVKDENR GPTLEVVVSR MKTVQSVSQT 120
LKNTSTAIPM RFVAVSATIP NAEDIAEWLS DGERPAVCLK MDESHRPVKL QKVVLGFPCS 180
SNQTEFKFDL TLNYKIASVI QMYSDQKPTL VFCATRKGVQ QAASVLVKDA KFIMTVEQKQ 240
RLQKYAYSVR DSKLRDILKD GAAYHHAGME LSDRKVVEGA FTVGDLPVLF TTSTLAMGVN 300
LPAHLVVIKS TMHYAGGLFE EYSETDILQM IGRAGRPQFD TTATAVIMTR LSTRDKYIQM 360
LACRDTVESS LHRHLIEHLN AEIVLHTITD VNIAVEWIRS TLLYIRALKN PSHYGFASGL 420
NKDGIEAKLQ ELCLKNLNDL SSLDLIKMDE GVNFKPTEAG RLMAWYYITF ETVKKFYTIS 480
GKETLSDLVT LIAGCKEFLD IQLRINEKKT LNTLNKDPNR ITIRFPMEGR IKTREMKVNC 540
LIQAQLGCIP IQDFALTQDT AKIFRHGSRI TRWLSDFVAA QEKKFAVLLN SLILAKCFRC 600
KLWENSLHVS KQLEKIGITL SNAIVNAGLT SFKKIEETDA RELELILNRH PPFGTQIKET 660
VMYLPKYELK VEQITRYSDT TAEILVTVIL RNFEQLQTKR TASDSHYVTL IIGDADNQVV 720
YLHKITDSVL LKAGSWAKKI AVKRALKSED LSINLISSEF VGLDIQQKLT VFYLEPKRFG 780
NQITMQRKSE TQISHSKHSD ISTIAGPNKG TTASKKPGNR ECNHLCKSKH TCGHDCCKIG 840
VAQKSEIKES TISSYLSDLR NRNAVSSVPP VKRLKIQMNK SQSVDLKEFG FTPKPSLPSI 900
SRSEYLNISE LPIMEQWDQP EIYGKVRQEP SEYQDKEVLN VNFELGNEVW DDFDDENLEV 960
TSFSTDTEKT KISGFGNTLS SSTRGSKLPL QESKSKFQRE MSNSFVSSHE MSDISLSNSA 1020
MPKFSASSMT KLPQQAGNAV IVHFQERKPQ NLSPEIEKQC FTFSEKNPNS SNYKKVDFFI 1080
RNSECKKEVD FSMYHPDDEA DEMKSLLGIF DGIF 1114 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 
Interpro
 IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase.
 IPR004179; Sec63-dom. 
Pfam
 PF00270; DEAD
 PF00271; Helicase_C
 PF02889; Sec63 
SMART
 SM00490; HELICc
 SM00973; Sec63 
PROSITE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER 
PRINTS