CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023746
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative RNA-binding protein Luc7-like 2 
Protein Synonyms/Alias
  
Gene Name
 LUC7L2 
Gene Synonyms/Alias
 CGI-59; CGI-74 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
122ISAEVAAKAERVHELacetylation[1]
166VEKARAKKREAEEVYmethylation[2]
Reference
 [1] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861]
 [2] Mass spectrometry-based identification and characterisation of lysine and arginine methylation in the human proteome.
 Bremang M, Cuomo A, Agresta AM, Stugiewicz M, Spadotto V, Bonaldi T.
 Mol Biosyst. 2013 Jul 30;9(9):2231-47. [PMID: 23748837] 
Functional Description
 May bind to RNA via its Arg/Ser-rich domain. 
Sequence Annotation
 MOD_RES 18 18 Phosphoserine.
 MOD_RES 111 111 Phosphothreonine.
 MOD_RES 266 266 5-hydroxylysine; by JMJD6.
 MOD_RES 269 269 5-hydroxylysine; by JMJD6.
 MOD_RES 383 383 Phosphoserine.
 MOD_RES 384 384 Phosphoserine.  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Hydroxylation; Nucleus; Phosphoprotein; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 392 AA 
Protein Sequence
MSAQAQMRAM LDQLMGTSRD GDTTRQRIKF SDDRVCKSHL LNCCPHDVLS GTRMDLGECL 60
KVHDLALRAD YEIASKEQDF FFELDAMDHL QSFIADCDRR TEVAKKRLAE TQEEISAEVA 120
AKAERVHELN EEIGKLLAKV EQLGAEGNVE ESQKVMDEVE KARAKKREAE EVYRNSMPAS 180
SFQQQKLRVC EVCSAYLGLH DNDRRLADHF GGKLHLGFIE IREKLEELKR VVAEKQEKRN 240
QERLKRREER EREEREKLRR SRSHSKNPKR SRSREHRRHR SRSMSRERKR RTRSKSREKR 300
HRHRSRSSSR SRSRSHQRSR HSSRDRSRER SKRRSSKERF RDQDLASCDR DRSSRDRSPR 360
DRDRKDKKRS YESANGRSED RRSSEEREAG EI 392 
Gene Ontology
 GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. 
Interpro
 IPR004882; LUC7-rel. 
Pfam
 PF03194; LUC7 
SMART
  
PROSITE
  
PRINTS