| Tag | Content |
|---|
| CPLM ID | CPLM-018541 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Aspartoacylase-2 |
Protein Synonyms/Alias | Acylase III; Aminoacylase III; Aminoacylase-3; ACY-3; Hepatitis C virus core-binding protein 1; HCBP1 |
Gene Name | Acy3 |
Gene Synonyms/Alias | Aspa2 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 91 | PDDPYEVKRARELNQ | ubiquitination | [1] | | 296 | EKHVAFLKSEKIRVT | ubiquitination | [1] | | 299 | VAFLKSEKIRVTVPA | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. |
Sequence Annotation | REGION 70 71 Substrate binding (Potential).
METAL 21 21 Zinc (Potential).
METAL 24 24 Zinc (Potential).
METAL 116 116 Zinc (Potential).
BINDING 63 63 Substrate (Potential).
BINDING 177 177 Substrate (Potential).
BINDING 287 287 Substrate (Potential). |
Keyword | 3D-structure; Cell membrane; Complete proteome; Cytoplasm; Hydrolase; Membrane; Metal-binding; Reference proteome; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 318 AA |
Protein Sequence | MSSLPGSREP LLRVAVTGGT HGNEMCGVYL ARYWLQNPGE LQRPSFSAMP VLANPAATAA 60
CCRYLDRDLN RSCTLTFLGS TATPDDPYEV KRARELNQLL GPKGTGQAFD FTLDLHNTTA 120
NTGVCLISES NISFNLHLCH YLQRQNPGMP CRLFLYEPAG TETFSVESIS KNGICLEMGP 180
QPQGVLRADL FSRMRALVAS ILDFIELFNQ GMDLPAFEMD IYRNLGSVDF PRTADGDLAG 240
TVHPQLQDHD FEPLRPGEPI FKLFSGEDVL YEGDSIVYPV FINEAAYYEK HVAFLKSEKI 300
RVTVPALLRL TPRSTQTP 318 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |