CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017202
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pleckstrin homology domain-containing family O member 2 
Protein Synonyms/Alias
 PH domain-containing family O member 2; Pleckstrin homology domain-containing family Q member 1; PH domain-containing family Q member 1 
Gene Name
 Plekho2 
Gene Synonyms/Alias
 Plekhq1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
7*MEEESIKEGSEKPRubiquitination[1]
37GGLLGLWKDRYLLLCubiquitination[1]
482ETPGLVQKRKELVTLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
 DOMAIN 18 120 PH.
 MOD_RES 233 233 Phosphothreonine.
 MOD_RES 236 236 Phosphoserine.
 MOD_RES 279 279 Phosphoserine.
 MOD_RES 395 395 Phosphoserine.  
Keyword
 Coiled coil; Complete proteome; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 495 AA 
Protein Sequence
MEEESIKEGS EKPRGARTAD KAGWIKKSSG GLLGLWKDRY LLLCQAQLLV YENEDEQKCV 60
ETVELGSYEK CQDLRTLLKR KHHRFILLRS PGNKVSDIKF QAPSGEEKES WIKALNEGIN 120
RGKNKAFDEV KVDKTCALEH VTRNRVRGGQ RRRPPTRIHL KEVASAASDG LSRLDLDVPD 180
SGPPVFAPLS DISEDQPQEP PRALMPPVKP SPGPETSAVE DSKETPAGER ALTPDSASSG 240
ANPESQEDAE TPAKEDSDVK SLPNSTLSEK LKVSWENPSP EKPSAPESAQ LSSSETPEAT 300
PRESKKPPAP PPKILSEKMK ACMSGVDASG SSQSSEAPET TSPEPTQVSV NGMDDGPESA 360
LQAMGIPGPA PEDAAASPAL PFSDLPSQFH PRSSSLGDLL RESPQHPRLP KEKLYRAQLE 420
VKVASKQTEK LLNQVLGSEP PPVCAESLLS QAVEQLRQAT QVLQEMRDLG ELNQETPGLV 480
QKRKELVTLY RRSAP 495 
Gene Ontology
 GO:0005543; F:phospholipid binding; IEA:InterPro. 
Interpro
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology. 
Pfam
 PF00169; PH 
SMART
 SM00233; PH 
PROSITE
 PS50003; PH_DOMAIN 
PRINTS