CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016785
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tetratricopeptide repeat protein 19, mitochondrial 
Protein Synonyms/Alias
 TPR repeat protein 19 
Gene Name
 Ttc19 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
241ARYLLFSKQLSQAQRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Mitochondrial protein required for formation of the mitochondrial complex III (By similarity). 
Sequence Annotation
 REPEAT 127 160 TPR 1.
 REPEAT 220 260 TPR 2.
 REPEAT 269 302 TPR 3.
 REPEAT 308 341 TPR 4.  
Keyword
 Alternative splicing; Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Repeat; TPR repeat; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 365 AA 
Protein Sequence
MFRLLRWRLG RTLLRAAGRR CGGCTARLLP ERTGDAGTGA ERLRTRGAPA RGHGVLPLLA 60
ALAWFSRPAA TAEQPGEDAS DEAEAEIIQL LKQAKLSIMK DEPEAAELIL HDALRLAYES 120
DNRKAITYTY DLMANLAFIR GQLENAEQLF KATMSYLLGG GMKQEDNAII EISLKLANIY 180
AAQNKQEFAL AGYEFCISTL EGKIEREKEL AEDIMSEETA NTYLLLGMCL DSCARYLLFS 240
KQLSQAQRMY EKALQICQEI QGERHPQTIV LMSDLATTLD AQGHFDDAYI YMQRASDLAR 300
EINHPELHMV LSNLAAILIH RERYTQAKEI YQEALKRAEL KRDEVSVQHI REELAELSRK 360
SRRLT 365 
Gene Ontology
 GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.
 GO:0034551; P:mitochondrial respiratory chain complex III assembly; ISS:UniProtKB. 
Interpro
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR013105; TPR_2. 
Pfam
 PF07719; TPR_2 
SMART
  
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS