CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020542
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 40S ribosomal protein S21 
Protein Synonyms/Alias
  
Gene Name
 Rps21 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
51GRFNGQFKTYGICGAubiquitination[1]
74DSILRLAKADGIVSKacetylation[2]
74DSILRLAKADGIVSKsuccinylation[2]
81KADGIVSKNF*****acetylation[2, 3]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654
Functional Description
  
Sequence Annotation
 MOD_RES 1 1 N-acetylmethionine (By similarity).
 MOD_RES 81 81 N6-acetyllysine (By similarity).  
Keyword
 Acetylation; Complete proteome; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 83 AA 
Protein Sequence
MQNDAGEFVD LYVPRKCSAS NRIIAAKDHA SIQMNVAEVD RTTGRFNGQF KTYGICGAIR 60
RMGESDDSIL RLAKADGIVS KNF 83 
Gene Ontology
 GO:0022627; C:cytosolic small ribosomal subunit; IBA:RefGenome.
 GO:0043022; F:ribosome binding; ISS:UniProtKB.
 GO:0003735; F:structural constituent of ribosome; IBA:RefGenome.
 GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:RefGenome.
 GO:0000461; P:endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:RefGenome.
 GO:0006414; P:translational elongation; IBA:RefGenome. 
Interpro
 IPR001931; Ribosomal_S21e.
 IPR018279; Ribosomal_S21e_CS. 
Pfam
 PF01249; Ribosomal_S21e 
SMART
  
PROSITE
 PS00996; RIBOSOMAL_S21E 
PRINTS