| Tag | Content |
|---|
| CPLM ID | CPLM-018546 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like |
Protein Synonyms/Alias | tRNA-dihydrouridine synthase 3-like |
Gene Name | Dus3l |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 403 | ALMNRSAKFQQIVRG | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity). |
Sequence Annotation | ZN_FING 107 137 C3H1-type 1.
ZN_FING 145 175 C3H1-type 2.
MOD_RES 260 260 Phosphothreonine (By similarity). |
Keyword | Alternative splicing; Complete proteome; FAD; Flavoprotein; Metal-binding; Oxidoreductase; Phosphoprotein; Reference proteome; Repeat; tRNA processing; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 637 AA |
Protein Sequence | MAETAAESGG GGDSGVGACE RGVAPIKAQY RTTKERFHEY LDGDKQEGAC QEVPTGDPAE 60
PGAKRIRLED GQENGKTEVA IESRERQVPK RARGQNKSRP HVKPAHYDKD RLCPSFLQEP 120
ATPCAFGDRC RFLHDVGRYL ETKPADLGPR CVLFETFGRC PFSMTCRFAG AHLGPEGQNL 180
VQEEVVARCA QLPSVRNGLD RALQQQLRKR QVCFERAEQA LNRLTQSPMP TVVPETTVAM 240
ATPKQNSCHA QLDTVGGAGT PQSSPVPTCG PLTDEDVIRL RPCEKKRLDI SGKLYLAPLT 300
TCGNLPFRRI CKRFGADVTC GEMAVCTNLL QGQMSEWALL KRHPCEDIFG VQLEGAFPDT 360
MTKCAELLNR TIDVDFVDIN VGCPIDLVYK KGGGCALMNR SAKFQQIVRG VNGVLDVPLT 420
VKMRTGVQER VSLAHRLLPE LRDWGVALVT LHGRSREQRY TRLADWPYIE QCAKVASPMP 480
LFGNGDILSF EDANCAMQTG VAGIMVARGA LLKPWLFTEI KEQRHWDISS SERLDILRDF 540
THYGLEHWGS DTQGVERTRR FLLEWLSFLC RYVPVGLLER PPQRINERPP YYLGRDYLET 600
LMASQQAADW IRISEMLLGP VPPGFVFLPK HKANAYK 637 |
Gene Ontology | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. GO:0003676; F:nucleic acid binding; IEA:InterPro. GO:0017150; F:tRNA dihydrouridine synthase activity; IEA:InterPro. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0002943; P:tRNA dihydrouridine synthesis; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |