| Tag | Content |
|---|
| CPLM ID | CPLM-014071 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Splicing factor, arginine/serine-rich 19 |
Protein Synonyms/Alias | SR-related and CTD-associated factor 1 |
Gene Name | Scaf1 |
Gene Synonyms/Alias | Sfrs19 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 55 | QGDLPNDKDGARCRG | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May function in pre-mRNA splicing (By similarity). |
Sequence Annotation | REGION 1131 1256 Necessary for interaction with the CTD
MOD_RES 240 240 Phosphoserine.
MOD_RES 328 328 Phosphothreonine.
MOD_RES 442 442 Phosphoserine (By similarity).
MOD_RES 447 447 Phosphoserine (By similarity).
MOD_RES 491 491 Phosphoserine (By similarity).
MOD_RES 493 493 Phosphoserine (By similarity).
MOD_RES 510 510 Phosphoserine.
MOD_RES 518 518 Phosphoserine.
MOD_RES 520 520 Phosphoserine (By similarity).
MOD_RES 577 577 Phosphoserine (By similarity).
MOD_RES 579 579 Phosphoserine (By similarity).
MOD_RES 691 691 Phosphoserine.
MOD_RES 695 695 Phosphoserine.
MOD_RES 821 821 Phosphoserine.
MOD_RES 876 876 Phosphoserine (By similarity).
MOD_RES 883 883 Phosphoserine (By similarity).
MOD_RES 912 912 Phosphoserine.
MOD_RES 923 923 Phosphothreonine (By similarity).
MOD_RES 936 936 Phosphothreonine.
MOD_RES 948 948 Phosphothreonine (By similarity). |
Keyword | Alternative splicing; Complete proteome; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Repeat; RNA-binding. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1256 AA |
Protein Sequence | MEEEDESRGK TEESGEDRGD GPPDRDPALS PSAFILRAIQ QAVGSSLQGD LPNDKDGARC 60
RGLRWRRCCR SPRSEPRSQE SGAADTATVL DTAADSFLVE LVSILDPPDT WVPSRLDLQP 120
GESEDMLELV AEVRIGDRDP MPLPVPSLFP RLRAWRTGKT VSPQSHASRP ACSRHLTLGT 180
GDGGPAPPPA PSSASSSPSP SPSSSSPSPP PPPPPPPPPA LPAPRFDIYD PFHPTDEAYS 240
PPPAPEQKYD PFEPTGSNPS SSAGTPSPEE EEEEEEEEEE EGLSQSISRI SETLAGIYDD 300
NSLSQDFPGD DSPRREPPPP QTLGAPGTPP QADSTRAEGA PRRRVFVLGP EAEACHEGKV 360
SVEVVTAGAP ALSLPPLPPT DPEIEEGEIV QPEEEPRVAV SLFRAARPRQ PPASVATLAS 420
VAAPAAPPAS APRAPEGDDF LSLHADSDGE GALQVDLGEP PAPPAADARW GGLDLRRKIL 480
TQRRERYRQR SASPGPPPAR KKARRERQRS GDPAPPDSPS WEAKKHRSRE RKLGSHSTAR 540
RRSRSRSRRR SRSRSADRRR GGHRSRSREK RRRRRRSASP PPAASSSSSS RRERHRGKRR 600
EGGKKKKKRS RSRAEKRSGD LEKLPASVPP SGSDRDSRRR GAVPPSIQDL TDHDLFAIKR 660
TITVGRPDKA EPRAPSPAPA VSPKREVLYD SEGLSADERG GKSDKDRRRS GAASSSSSSR 720
EKGSRRKALD GDRGRDRDRS SKKTRPPKDS TPGSGPLPKA PPSSGSSSSS SSCSSRKVKL 780
QSKVAVLIRE GVSSTTPAKD SSSSGLGSIG VKFSRDRESR SPFLKPDERA PAEVAKVAPG 840
SNKPKKTKAK AKAGAKKAKG TKGKTKPSKT RKKVRSGGSS TASGGPGSLK KSKADSCSQA 900
ASAKGTEETS WSGEERTTKA PSTPPPKVAP PPPALTPDSQ TVDSSCKTPE VSFLPEEASE 960
DTGVRVGAEE EEEEEEEEEE EEEQQPATTT ATSTAAAAPS TAPSAGSTAG DSGAEDGPAA 1020
RISQLPTLPP PMPWNLPAGV DCTTSGVLAL TALLFKMEEA NLASRAKAQE LIQATNQILS 1080
HRKPSSTLGV TPAPVPTSLG LPPGPSSYLL PGSLPIGGCG STPPTPTGLA PASDKREGSS 1140
SSEGRGDTDK YLKKLHTQER AVEEVKLAIK PYYQKKDITK EEYKDILRKA VHKICHSKSG 1200
EINPVKVSNL VRAYVQRYRY FRKHGRKPGD PPGPPRPPKE PGPPDKGGPG LPLPPL 1256 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003723; F:RNA binding; IEA:UniProtKB-KW. GO:0006397; P:mRNA processing; IEA:UniProtKB-KW. GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. GO:0006366; P:transcription from RNA polymerase II promoter; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |