CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002194
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Major urinary protein 3 
Protein Synonyms/Alias
 MUP 3; Non-group 1/group 2 MUP15 
Gene Name
 Mup3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
130IMIHLINKKDGKTFQubiquitination[1]
153PDLSLDIKEKFAKLCubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Binds pheromones that are released from drying urine of males. These pheromones affect the sexual behavior of females. 
Sequence Annotation
 CARBOHYD 66 66 N-linked (GlcNAc...).
 DISULFID 86 179 By similarity.  
Keyword
 Complete proteome; Disulfide bond; Glycoprotein; Pheromone-binding; Reference proteome; Secreted; Signal; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 184 AA 
Protein Sequence
MKLLLPLLLL LCLELTLVCI HAEESSSMER NFNVEQISGY WFSIAEASYE REKIEEHGSM 60
RAFVENITVL ENSLVFKFHL IVNEECTEMT AIGEQTEKAG IYYMNYDGFN TFSILKTDYD 120
NYIMIHLINK KDGKTFQLME LYGREPDLSL DIKEKFAKLC EEHGIIRENI IDLTNVNRCL 180
EARE 184 
Gene Ontology
 GO:0005829; C:cytosol; ISS:UniProtKB.
 GO:0005615; C:extracellular space; ISS:UniProtKB.
 GO:0005634; C:nucleus; ISS:UniProtKB.
 GO:0005009; F:insulin-activated receptor activity; ISS:UniProtKB.
 GO:0005550; F:pheromone binding; ISS:UniProtKB.
 GO:0036094; F:small molecule binding; IEA:InterPro.
 GO:0005215; F:transporter activity; IEA:InterPro.
 GO:0009060; P:aerobic respiration; ISS:UniProtKB.
 GO:0071396; P:cellular response to lipid; ISS:UniProtKB.
 GO:0006112; P:energy reserve metabolic process; ISS:UniProtKB.
 GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
 GO:0031649; P:heat generation; ISS:UniProtKB.
 GO:0045475; P:locomotor rhythm; ISS:UniProtKB.
 GO:0070584; P:mitochondrion morphogenesis; ISS:UniProtKB.
 GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.
 GO:0061179; P:negative regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.
 GO:0051055; P:negative regulation of lipid biosynthetic process; ISS:UniProtKB.
 GO:0010888; P:negative regulation of lipid storage; ISS:UniProtKB.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
 GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
 GO:0010907; P:positive regulation of glucose metabolic process; ISS:UniProtKB.
 GO:0045834; P:positive regulation of lipid metabolic process; ISS:UniProtKB.
 GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.
 GO:0035634; P:response to stilbenoid; IEP:UniProtKB. 
Interpro
 IPR012674; Calycin.
 IPR011038; Calycin-like.
 IPR002345; Lipocalin.
 IPR022272; Lipocalin_CS.
 IPR000566; Lipocln_cytosolic_FA-bd_dom.
 IPR002971; Maj_urinary. 
Pfam
 PF00061; Lipocalin 
SMART
  
PROSITE
 PS00213; LIPOCALIN 
PRINTS
 PR00179; LIPOCALIN.
 PR01221; MAJORURINARY.