UniProt Accession

 MYOZ2_MOUSE; Q9JJW5 

Genbank Protein ID

 AY013296; AJ252148; BC024360 

Genbank Nucleotide ID

 AAG38939.1; CAB92972.1; AAH24360.1 

Protein Name

 Myozenin-2 

Protein Synonyms/Alias

 Calsarcin-1; FATZ-related protein 2 

Gene Name

 Myoz2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
9	LSHSAMVKQRKQQAS	ubiquitination	[1]
34	VDGMDLGKKVSIPRD	ubiquitination	[1]
67	MRQRRSDKYTFENFQ	ubiquitination	[1]
132	PGYSGPLKEIPPERF	ubiquitination	[1]
146	FNTTAVPKYYRSPWE	ubiquitination	[1]
176	KLFKPEGKAELRDYR	ubiquitination	[1]
197	TPFGGFEKASKMVKF	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis. 

Sequence Annotation

 MOD_RES 111 111 Phosphothreonine.  

Keyword

 Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 264 AA 

Protein Sequence

Gene Ontology

 GO:0015629; C:actin cytoskeleton; IDA:MGI.
 GO:0030018; C:Z disc; IDA:MGI. 

Interpro

 IPR008438; Calsarcin-bd. 

Pfam

 PF05556; Calsarcin 

SMART

  

PROSITE

  

PRINTS