CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004276
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Aspartate aminotransferase 
Protein Synonyms/Alias
 AspAT; Transaminase A 
Gene Name
 aspC 
Gene Synonyms/Alias
 SSO0897 
Created Date
 July 27, 2013 
Organism
 Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322  
NCBI Taxa ID
 273057 
Lysine Modification
Position
Peptide
Type
References
203VDISRDNKIILLSDEmethylation[1]
385AVNEEVIKEGIQKIRmethylation[1]
Reference
 [1] Update on activities at the Universal Protein Resource (UniProt) in 2013.
 e="String">UniProt Consortium.
 Nucleic Acids Res. 2013 Jan;41(Database issue):D43-7. [PMID: 23161681] 
Functional Description
  
Sequence Annotation
 BINDING 43 43 Aspartate; via amide nitrogen (By
 BINDING 181 181 Aspartate (By similarity).
 BINDING 374 374 Aspartate (By similarity).
 MOD_RES 203 203 N6-methyllysine; partial.
 MOD_RES 242 242 N6-(pyridoxal phosphate)lysine.
 MOD_RES 385 385 N6-methyllysine; partial.  
Keyword
 Aminotransferase; Complete proteome; Cytoplasm; Direct protein sequencing; Methylation; Pyridoxal phosphate; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 402 AA 
Protein Sequence
MVSLLDFNGN MSQVTGETTL LYKEIARNVE KTKKIKIIDF GIGQPDLPTF KRIRDAAKEA 60
LDQGFTFYTS AFGIDELREK IAQYLNTRYG TDVKKEEVIV TPGAKPALFL VFILYINPSD 120
EVILPDPSFY SYAEVVKLLG GKPIYANLKW SREEGFSIDV DDLQSKISKR TKMIVFNNPH 180
NPTGTLFSPN DVKKIVDISR DNKIILLSDE IYDNFVYEGK MRSTLEDSDW RDFLIYVNGF 240
SKTFSMTGWR LGYIVAKREI IQKMGILAAN VYTAPTSFVQ KAAVKAFDTF DEVNQMVSLF 300
KKRRDVMYDE LTKVKGVEVS KPNGAFYMFP NVSKILKTSG FDVKSLAIKL IEEKGVVTIP 360
GEVFPLNIGK EFLRLSFAVN EEVIKEGIQK IREFAEQMMN SR 402 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004069; F:L-aspartate:2-oxoglutarate aminotransferase activity; IEA:EC.
 GO:0080130; F:L-phenylalanine:2-oxoglutarate aminotransferase activity; IEA:EC.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0009058; P:biosynthetic process; IEA:InterPro. 
Interpro
 IPR004839; Aminotransferase_I/II.
 IPR004838; NHTrfase_class1_PyrdxlP-BS.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1.
 IPR015422; PyrdxlP-dep_Trfase_major_sub2. 
Pfam
 PF00155; Aminotran_1_2 
SMART
  
PROSITE
 PS00105; AA_TRANSFER_CLASS_1 
PRINTS