CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028011
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Signal recognition particle subunit SRP72 
Protein Synonyms/Alias
  
Gene Name
 Srp72 
Gene Synonyms/Alias
 Srp72-RA; CG5434; Dmel_CG5434 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
67SKFEEAYKFIEKNRLacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
 Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Reference proteome; Ribonucleoprotein; Signal recognition particle. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 650 AA 
Protein Sequence
MSKDANPKEA LIKAAYADVN KFGNNQEFDK AVKAVNRILG VAPDDPTALH CKVVCLVQLS 60
KFEEAYKFIE KNRLSSLFFE KAYCEYQLNK QQQALKTIDD AGLQPLPPNL KELRTQVLYR 120
LERYDECLDS YRDIIKNTSD EYEEERRTNL SAVAANLAVD QTKEVPEVPE DTYEQYFNSA 180
CIQANRQKYA EAERKLRTSE KLCLEDECAS EEEIIEEVDV IRVQLAYVLQ LQGKTKEASS 240
IYADCLRHKP KDAALVAVAS NNLVVVNKDQ NVFDSKKKIR AALADACESR LTSRQKQVIA 300
LNNCLLALYT NAGDQVQQLS QKLAQTYPQV EFEALLIRCT QLAKDRKHKE AIEQLQKFAA 360
AHKSHEFVSK FAIIQLQLLQ GNRKDAIETL LSLGEAKYKP GVVSALVSLY LGTDNKTAAS 420
ALLKSAVDWY KKNEVSSGDL SDMWRQAAEF HLRGGASETA ASSLEELLKL NPNDTKVLAQ 480
LVIAYAQFQP KRALELSRKL PKLETLTTAS EIDALEAANW VMSAKAAKKT ANTKVEPSPS 540
TPLEKKKNRN RKRKGKLPKN YNAEVAPDPE RWLPKYERTG FRKKRGGARG KDVIKGSQGM 600
ASGAADQYDM SSRVNLTKNS PATPVYQETA PGPRQQHRKG GHKKKKGGRF 650 
Gene Ontology
 GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IEA:UniProtKB-KW.
 GO:0008312; F:7S RNA binding; IEA:InterPro.
 GO:0033227; P:dsRNA transport; IMP:FlyBase.
 GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro. 
Interpro
 IPR013699; Signal_recog_part_SRP72_RNA-bd.
 IPR026270; SRP72.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF08492; SRP72 
SMART
  
PROSITE
 PS50005; TPR 
PRINTS