CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031913
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CG3011, isoform B 
Protein Synonyms/Alias
  
Gene Name
 CG3011, Dmel_CG3011 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
317AYQTQVLKNAKALCDacetylation[1]
427AKLAGSPKITDYHKTacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
 Interconversion of serine and glycine (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; One-carbon metabolism; Pyridoxal phosphate; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 467 AA 
Protein Sequence
MADQKLLQTP LAQGDPELAE LIKKEKERQR EGLEMIASEN FTSVAVLESL SSCLTNKYSE 60
GYPGKRYYGG NEYIDRIELL AQQRGRELFN LDDEKWGVNV QPYSGSPANL AVYTGVCRPH 120
DRIMGLDLPD GGHLTHGFFT PTKKISATSI FFESMPYKVN PETGIIDYDK LAEAAKNFRP 180
QIIIAGISCY SRLLDYARFR QICDDVGAYL MADMAHVAGI VAAGLIPSPF EWADIVTTTT 240
HKTLRGPRAG VIFFRKGVRS TKANGDKVLY DLEERINQAV FPSLQGGPHN NAVAGIATAF 300
KQAKSPEFKA YQTQVLKNAK ALCDGLISRG YQVATGGTDV HLVLVDVRKA GLTGAKAEYI 360
LEEVGIACNK NTVPGDKSAM NPSGIRLGTP ALTTRGLAEQ DIEQVVAFID AALKVGVQAA 420
KLAGSPKITD YHKTLAENVE LKAQVDEIRK NVAQFSRKFP LPGLETL 467 
Gene Ontology
 GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0048149; P:behavioral response to ethanol; IMP:FlyBase.
 GO:0006544; P:glycine metabolic process; IEA:InterPro.
 GO:0006563; P:L-serine metabolic process; IEA:InterPro.
 GO:0035999; P:tetrahydrofolate interconversion; IEA:UniProtKB-UniPathway. 
Interpro
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1.
 IPR015422; PyrdxlP-dep_Trfase_major_sub2.
 IPR001085; Ser_HO-MeTrfase.
 IPR019798; Ser_HO-MeTrfase_PLP_BS. 
Pfam
 PF00464; SHMT 
SMART
  
PROSITE
 PS00096; SHMT 
PRINTS