CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026653
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Fumarate hydratase, class I 
Protein Synonyms/Alias
  
Gene Name
 fumA 
Gene Synonyms/Alias
 RPA3876 
Created Date
 July 27, 2013 
Organism
 Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) 
NCBI Taxa ID
 258594 
Lysine Modification
Position
Peptide
Type
References
203KGGGSANKSFLFQATacetylation[1]
Reference
 [1] System-wide studies of N-lysine acetylation in Rhodopseudomonas palustris reveal substrate specificity of protein acetyltransferases.
 Crosby HA, Pelletier DA, Hurst GB, Escalante-Semerena JC.
 J Biol Chem. 2012 May 4;287(19):15590-601. [PMID: 22416131] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Lyase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 551 AA 
Protein Sequence
MNAPTPIPSA ATPVPPYKHT PLFPLGKDET VYRKITSDGV RVEKVLGRDM LVVEREALRA 60
LSEAAFGEIN HYLRPGHLKQ LRAILDDPEA SPNDKFVALD FLKNANIAAG GVLPMCQDTG 120
TAIIMGKKGS NVITDGDDEA ALSEGARDAY LRRNLRYSQV APLSMFEEKN TANNMPAQCE 180
IYAEGDDAYK FMFMAKGGGS ANKSFLFQAT PSLLTRDRLL AFLKEKIMTL GTAACPPYHL 240
AIVIGGTSVE TTMKTVKLAS ARYLDALPTH GSELGNAFRD VEMEQEIHKM TQSLGVGAQF 300
GGKYFCHDVR VIRLPRHGAS LPIGLGVSCS ADRQMVGKIT KDGVYLEELE HNPAQYLPEV 360
EQALGGEVVK IDLNQPMKDI LATLSKHPIK TRLSLTGTMI VARDAAHAKL RDRLEKGEPL 420
PDYFKNHPVY YAGPAKTPDG YASGAFGPTT AGRMDSFVDQ FQAAGGSMVM VAKGNRAPAV 480
REACKKYGGF YLGSIGGAAA NLAEHCIKKV EVLEYPELGM EAIWKIDVVD FPAFIIVDDK 540
GNDFFKELNL G 551 
Gene Ontology
 GO:0004333; F:fumarate hydratase activity; IEA:EC.
 GO:0006091; P:generation of precursor metabolites and energy; IEA:InterPro. 
Interpro
 IPR004646; Fe-S_hydro-lyase_TtdA-typ_cat.
 IPR004647; Fe-S_hydro-lyase_TtdB-typ_cat.
 IPR011167; Fe_dep_fumarate_hydratase.
 IPR020557; Fumarate_lyase_CS. 
Pfam
 PF05681; Fumerase
 PF05683; Fumerase_C 
SMART
  
PROSITE
 PS00163; FUMARATE_LYASES 
PRINTS