UniProt Accession

 I3L449_HUMAN; I3L449 

Genbank Protein ID

 AC009087; AC009127 

Genbank Nucleotide ID

  

Protein Name

 Dihydroorotate dehydrogenase (quinone), mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 DHODH 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
85	EVRVLGHKFRNPVGI	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 193 AA 

Protein Sequence

Gene Ontology

 GO:0004152; F:dihydroorotate dehydrogenase activity; IEA:InterPro.
 GO:0006207; P:'de novo' pyrimidine nucleobase biosynthetic process; IEA:InterPro.
 GO:0006222; P:UMP biosynthetic process; IEA:InterPro. 

Interpro

 IPR013785; Aldolase_TIM.
 IPR012135; Dihydroorotate_DH_1_2.
 IPR001295; Dihydroorotate_DH_CS. 

Pfam

 PF01180; DHO_dh 

SMART

  

PROSITE

 PS00911; DHODEHASE_1 

PRINTS