| Tag | Content |
|---|
| CPLM ID | CPLM-019051 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ribulose-phosphate 3-epimerase |
Protein Synonyms/Alias | Ribulose-5-phosphate-3-epimerase |
Gene Name | RPE |
Gene Synonyms/Alias | HUSSY-17 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 223 | VCSEAAQKRSLDR** | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate. |
Sequence Annotation | REGION 146 149 Substrate binding.
REGION 197 198 Substrate binding.
ACT_SITE 37 37 Proton acceptor (Probable).
ACT_SITE 175 175 Proton donor (Probable).
METAL 35 35 Divalent metal cation.
METAL 37 37 Divalent metal cation.
METAL 70 70 Divalent metal cation.
METAL 175 175 Divalent metal cation.
BINDING 10 10 Substrate.
BINDING 70 70 Substrate.
BINDING 177 177 Substrate; via amide nitrogen. |
Keyword | 3D-structure; Alternative splicing; Carbohydrate metabolism; Cobalt; Complete proteome; Iron; Isomerase; Manganese; Metal-binding; Reference proteome; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 228 AA |
Protein Sequence | MASGCKIGPS ILNSDLANLG AECLRMLDSG ADYLHLDVMD GHFVPNITFG HPVVESLRKQ 60
LGQDPFFDMH MMVSKPEQWV KPMAVAGANQ YTFHLEATEN PGALIKDIRE NGMKVGLAIK 120
PGTSVEYLAP WANQIDMALV MTVEPGFGGQ KFMEDMMPKV HWLRTQFPSL DIEVDGGVGP 180
DTVHKCAEAG ANMIVSGSAI MRSEDPRSVI NLLRNVCSEA AQKRSLDR 228 |
Gene Ontology | GO:0005829; C:cytosol; TAS:Reactome. GO:0043231; C:intracellular membrane-bounded organelle; IEA:Compara. GO:0046872; F:metal ion binding; IDA:UniProtKB. GO:0048029; F:monosaccharide binding; IEA:Compara. GO:0004750; F:ribulose-phosphate 3-epimerase activity; IDA:UniProtKB. GO:0006098; P:pentose-phosphate shunt; IDA:UniProtKB. GO:0009052; P:pentose-phosphate shunt, non-oxidative branch; IEA:Compara. |
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SMART | |
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PRINTS | |