CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016361
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 RING finger protein 214 
Protein Synonyms/Alias
  
Gene Name
 Rnf214 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
153SGNCSEEKCPAASVLacetylation[1]
561KLEKILEKLLTRFPQacetylation[1]
582TNILQQIKTARTTMAubiquitination[2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 ZN_FING 623 665 RING-type; atypical.
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 497 497 Phosphoserine (By similarity).
 MOD_RES 511 511 Phosphoserine (By similarity).
 MOD_RES 516 516 Phosphoserine (By similarity).  
Keyword
 Acetylation; Alternative splicing; Coiled coil; Complete proteome; Metal-binding; Phosphoprotein; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 668 AA 
Protein Sequence
MAASEVAGLG AGTPSPSESS ALCASKSDES LPDGLSPKDS AQKQKNLSPP SVSSQMITKE 60
SNRNAHLEHP EQNPGSSVGD TSAAHEEVVG ENLVATALCL SGNGSQSDLK DLTNPAGEEG 120
DTSLRESLHP VTRSLKAGCH SKQLASGNCS EEKCPAASVL KEGSRDAGLD LLPVVPPANG 180
VEGVRVDQDD DQDSSSLKLS QNIAVQTDFK TADSEVNTDQ DIEKNLDKMM TERTLLKERY 240
QEVLDKQRQV ESQLQVQLKQ LQQRREEEMK NHQEILKAIQ DVTIKREETK KKIEKEKKEF 300
LQKEQDLKAE IEKLCEKGRR EVWEMELDRL KNQDGEINRN IMEETERAWK AEILSLESRK 360
ELLVLKLEEA EKEAELHLTY LKSTPPTLET VRSKQEWETR LNGVRIMKKN VRDQFNSHIQ 420
LVRNGAKLSS LPQIPTPTLP PPPSEADFML QVFQPSPSLT PRMPFSIGQV TMPMVMPSAD 480
PRSLSFPILN PALSQSSQPS PPLPGSHGRN SPGLGSLVSP HGPHMPPAAS IPPPPGLGGI 540
KASSETPRPQ PVDKLEKILE KLLTRFPQCN KAQMTNILQQ IKTARTTMAG LTMEELIQLV 600
AARLAEHERV ASSTQAPPTC KLCLMCQKLV QPSELHPMAC THALHKECIK FWAQTNTNDT 660
CPFCPTLK 668 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
  
SMART
 SM00184; RING 
PROSITE
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 
PRINTS