UniProt Accession

 TID_DROME; Q27237; O02528; O02529; O02549; Q24554; Q27259; Q7KVH8; Q8T9A7; Q9W1K7 

Genbank Protein ID

 X95241; X95242; X95247; X95249; X95251; Y10074; Y10074; X77822; X98094; AE013599; AE013599; AY069853 

Genbank Nucleotide ID

 CAA64528.1; CAA64531.1; CAA64536.1; CAA64538.1; CAA64540.1; CAA71163.1; CAA71164.1; CAA54837.1; CAA66720.1; AAF47051.3; AAS64764.1; AAL39998.1 

Protein Name

 Protein tumorous imaginal discs, mitochondrial 

Protein Synonyms/Alias

 Protein lethal(2)tumorous imaginal discs; TID50; TID56 

Gene Name

 l(2)tid 

Gene Synonyms/Alias

 CG5504 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
90	KAYYQLAKKYHPDTN	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

 May act as a tumor suppressor in larval imaginal disks. 

Sequence Annotation

 DOMAIN 65 130 J.
 REPEAT 227 234 CXXCXGXG motif; approximate.
 REPEAT 244 251 CXXCXGXG motif.
 REPEAT 266 273 CXXCXGXG motif; approximate.
 REPEAT 280 287 CXXCXGXG motif.
 ZN_FING 214 292 CR-type.
 METAL 227 227 Zinc 1 (By similarity).
 METAL 230 230 Zinc 1 (By similarity).
 METAL 244 244 Zinc 2 (By similarity).
 METAL 247 247 Zinc 2 (By similarity).
 METAL 266 266 Zinc 2 (By similarity).
 METAL 269 269 Zinc 2 (By similarity).
 METAL 280 280 Zinc 1 (By similarity).
 METAL 283 283 Zinc 1 (By similarity).  

Keyword

 Alternative splicing; Chaperone; Complete proteome; Developmental protein; Membrane; Metal-binding; Mitochondrion; Mitochondrion outer membrane; Polymorphism; Reference proteome; Repeat; Transit peptide; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 520 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:FlyBase.
 GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
 GO:0005739; C:mitochondrion; IDA:FlyBase.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
 GO:0006457; P:protein folding; IEA:InterPro.
 GO:0009408; P:response to heat; IEA:InterPro.
 GO:0007224; P:smoothened signaling pathway; IGI:FlyBase. 

Interpro

 IPR012724; DnaJ.
 IPR002939; DnaJ_C.
 IPR001623; DnaJ_domain.
 IPR018253; DnaJ_domain_CS.
 IPR008971; HSP40/DnaJ_pept-bd.
 IPR001305; HSP_DnaJ_Cys-rich_dom. 

Pfam

 PF00226; DnaJ
 PF01556; DnaJ_C
 PF00684; DnaJ_CXXCXGXG 

SMART

 SM00271; DnaJ 

PROSITE

 PS00636; DNAJ_1
 PS50076; DNAJ_2
 PS51188; ZF_CR 

PRINTS

 PR00625; JDOMAIN.