Tag | Content |
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CPLM ID | CPLM-031763 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ubiquitin carboxyl-terminal hydrolase |
Protein Synonyms/Alias | |
Gene Name | TGME49_055180, TGVEG_079210 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Toxoplasma gondii |
NCBI Taxa ID | 5811 |
Lysine Modification | Position | Peptide | Type | References |
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618 | PGASGIGKKKNENAY | acetylation | [1] |
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Reference | [1] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii. Xue B, Jeffers V, Sullivan WJ, Uversky VN. Mol Biosyst. 2013 Apr 5;9(4):645-57. [ PMID: 23403842] |
Functional Description | |
Sequence Annotation | |
Keyword | Complete proteome; Hydrolase; Protease; Reference proteome; Thiol protease; Ubl conjugation pathway. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 4187 AA |
Protein Sequence | MDELGDSVLQ QDAAAPASST FARCDQTATG REPSLSASVL QGSPQRTGVD ISRRWASESP 60 LASSSAATLS LCPVDQIRKT SKRTGSSRGD DRVERSVQES AWTPCSEKSE ASGAAHAGSR 120 SRHSPICSVV FTSPPAAVAP PSKASAASAV SGLCLQPEGS TPERLRVAQG AAPKVSPLED 180 GIPVATVKLA GLETCRTDHP HSPAAPQLAP QHQAPSEELN VSARLHTETR IQANDISVSH 240 ASASGSLPPL PSVAFFLHRA ASTCALASHA SSSDDGSAAR PSVQGICGPE KPNARQTGSS 300 EHELSPSISS TLSVSNSGAL SPRRSRGCTA FGQTGTFISP PTACSSRLSP RGGRQERQLA 360 GTKGELTEME AAFGAETKTE RERVSARGTE RELEFGDKPM EMTQESWRVE SGDVEERDSG 420 VESDLSGDAR QKGEKTAAVA TEVHPMQTDA APRLGGGTRQ LHQEGQHVMS SGECLAGLLW 480 PRDQLSLSVT ASRTARVSST HQKESLGEAR EEKPSGPDTL QPTSKEGFSQ TAQDSEQLSP 540 VHVAPSSLSE QCCLGDLLFM YNLRHSFAVP RESQQDAHPM SVFGLGEFKT GVWGKGGQGG 600 PGGGAGGASG PGASGIGKKK NENAYSLQRE LQQQQMAVRW LLSVTGNGSS ETSATGALPR 660 RSRLARMSPV SKAFGAVSAK HEPAGQAASA LFSGSSSSAS AVTSAPGLPG DQRGPEACES 720 TMKRERAACE DSGGVPSVSS HGRTGWEQKS EQAAILGATG LRKCRYVGLE NLGATCYLNV 780 YLQTLFMNVH FRDFLLSLPT LRELEEMERQ RPAEASRLSL APSTPETHSQ VLARQPREGR 840 TRQYSRGAED KKSQAEESDE TGSRDAETAD GEFPESPEPR CKIEERETHM KQDAEERGRP 900 QVKEESPKES TGARTEKTAL VPKENPPEAE RLDVAPPSAT SSVPEPFTPV FSASSPACLT 960 HGGGRAEAVD QENQADSRAR WCNWREKVKG QDVCTVLCSQ RYSLISSLQT IFAKLQEGIQ 1020 AAVRPSVVAD LLAEDLSYQE DANELQHRLF ELLESELGGR ESPLDFLRVL FGGRSRQTVK 1080 CSHCMYSGNK EEYFFQLNCC HKKSHQSGKH EPGDRNSRNS PEETEASRSP SLPLSSSPFS 1140 PEGDLASQEA DDSRAVTSPK QVAASTSSRC GPCPLSSLPA SQGESLSSSQ EDSTCAPASG 1200 PVDSDVAAVS TSRPEQSESK RHGRRGKRGP QRGAAASAHT GAGGQQGGTQ GTAGGRRREG 1260 RDSCERKGEA SSTSARGPGR KGVSAGQGRR PVDENKGGWK LEEDMARQYQ RTENLRGDSE 1320 YFCPQCGEKR EAKKRSQLSL LPPYLQLVVL RYSIDVKKQT GEWVRRKIHE ALEIPLVMDV 1380 RGCCTDDCQI GHLDGTLSSL RDASHAAHQY HLFGILEHQG ASATSGHYVA ITRDLRERAA 1440 GRSECADAAS VDDSKKTFLA SSLSDGDASA SLSQTTEAAS PLLPQDDGDR VQGCVSVGDW 1500 REAAPLGEGT LPRQLAPSGL EFLGSPRVCP GRGGEGGAQK VKACALPAEG ERRSDEDRRR 1560 SNADRICYAG GPEGKDACGK EAEGPSFSVD SPQQAPGKLV PAKGFEGDEG RDVTIASSTV 1620 ERDLSSQSVS PPRRGTSASR RKGSLREGYG SPPFLEPTKG FPGVATAAVL LGDADATTSP 1680 ITRDRDAFVF RDPSPFASPR PRWSAPLNGP NETAPEPNSV TVVVDVDASS PSLTVSAGSS 1740 SCSSGLASFP HRSLTPRLCS FPHPSTSVEK TVDKDYLRSG FAAATDACSA ETSSAPGPGA 1800 LPNFPTHASP SSSILSCGLN SSPADSSTSP SLKPYDGAGE TTNEDACVEV CEEPFLTHTP 1860 QAEKSRGRSQ AEALDASTLS PTTVTQKDLF SLEFKSPRSR HAALGRLSTW VAAPEPNAVE 1920 ARESGRGDRK RVEALEAQKG SCGPKKKGNA SLTQRTLDQY VGRTRAQVRG RDTGCTARKG 1980 GSSPCVSTAS PPRLASSPPG GAATCWSRES PDKKRRKREA ERGREEQTKR KADQLQRCTG 2040 RDCTQAVGDR QSRSGGKKEK QGGENSVSLV VVETPEEEDD DTDVEEEFVI LASPFQHEAS 2100 RQSAHETRHE NGSSQVAEAD EFYQGKEPQM KTALNKLTTR SLAVDDDLEE IPEVILGAGL 2160 PAEKKQPFGV QPEPSDNADK GRSTSDVVET KAAPQTAATR WSWVRFDDSE EGEWRRATPE 2220 AERVGATSRA PVGRSFSAGP LRIYSRTVYM VTYIRADLTA EETDMPLPRE LQDFIDEEVS 2280 ARTGREGEAG QRAALDENER AKERLTKNER ICEEQETLSM RQQTLLAYVQ QRQAALQQLL 2340 RHALPSALKE LEQQRLERVQ KEALHGEVVR ARLPSPVCER NLVNIQQRLS LLPQLRQLSF 2400 IPRSWWQQFV RGIDYPTMST SLPPSLLPRR DSNNRNGICM VPLTKAENGD GNRPARKRKK 2460 NNAEQRGAAG SSREKSEDEL RERGRLGAPG EEHATAGESE LEGSANAGAK KEAKEEDLRG 2520 LSICEVLEGE TREGRQQSRS AMKSEEAAIS GHRQQWLQTS GGGRDAYSRA ANAQEEVKAY 2580 RQLEQSYADG GTTSEETREG RDGDATSPAC RSENDKEKGV IDYSSILCPH YRNALAASIS 2640 CSPAAAGTVV SPQDALVTSS LSMPALPLNA SSFHEAHRPW IFNSISEPDE EKLLAEPSYP 2700 IEKLLRVTDF CGERGVDPLS IWTGEAKAIP TALFSDLLAA SALRPSIPDP SLLPNLCSVC 2760 SAALSGLVDF YSEQHRSIEA ILEALKRQKT IPTVCEETPV SPELVESSSA CAIPSSTANL 2820 SSPPKEVTVS STANGEADRA EGVHLQFVHA GGDGDTAPAR SESSQETEKN QEETIHAEVL 2880 PSIVVPLPSP DDVHLRSSSQ EPSASSVAPG DQQQGGEKEE TQGGRQISCV ASPCGVGALS 2940 PIVCAGVDEV PDSSKVAPVQ DAEGNRQVSV SSSQSRVEGS GPDSGDNQRL ETEEPLSPRI 3000 LNEHETPATD LLGCCIPSAS LSSSPRAAVP ALNPWVLEHT ATLPEFIYVS RRPLQRAFSL 3060 HSCFLTLCTL PTASSPASIP FSALLPSSSS PQSRELKVLR AKMKREGKDS REKYLSWLTL 3120 SDVRREVTLG RKLPQGDSDP SRGVKPPKKD ARKDGDWERA EEGIEEGEAS DGDGTNDGRR 3180 RRRKKVEDEE QGEEQVCGDE DVEDVNMDDE GEESASLGSL LHAEDEGNAT KKTRVTRARK 3240 AVSSPPGANR KAVAHTLHRA TSRPRSDHKQ EENEDLEEEE GNTEEGQGNS QDAHTGRDNV 3300 FDFASDLLCC HQKLRIQGAV GKSNKLQRFL VNKVPTAAIL NFLYFEREKA VLYRELGIAN 3360 PVTFDCSTFV SQYAQECSIC LTEQQAEQQR RQVWRDKRNE ESKALGQIIG KRWRLRKETG 3420 PASRLATPLP KKGRFFFVST EWRHQWLSYV ASGCETEGVT SKPPPLLNSS LLCDCPTRGL 3480 KVDPTDTLLS PTFLADPPES ETDTYILVHE DDVDLLERFG LTGFKTAENL SMCVEVKHIP 3540 GEIASSLLPP SSSPSSRLAA SPCFAGPVPA FFFPSLAPCS ACVRTHRIEQ GFYDFPPVDL 3600 SFHLRQNRWN GDAPEVKSEP ETVREAGPGR GRGNTGNGGR RQASSRVLGQ KKITVRVSGE 3660 TEIASLLAHV VASMTEAEET KETTVYLEGP PRHVFYFSPK SSCLSVSIPD AGPTASPPNR 3720 SVYPSTSPTT TDTLPRTAPS LICNAAAAHS PPAAPRRYSG HREEGKDTQL LGDLCDGRAV 3780 TRPLCLSPSG ARQKERHENR EACDVLCLER TERATTENEA EPRGERESQS QAEISTRPLV 3840 SFVDEEVGKA VKADASGTRV RLPEETYTGS EHSGITLRAV SLPHSCCLSL EVEMKTHLRD 3900 LLLYVNEAWQ VSYEFQESRQ LDEVRREKAV RKEAEAATED EAALVSVALQ EGGFLEAEEG 3960 TRRRQADREA TERVLEIQDS EKEDDGGSAG EASQVEECVE VQDASTSAEK LARKPLSPLP 4020 GDSLVRNKRE RSEEPEPVDV LTDGEEQEEL AQSDQKKSRF ATTHPTSQGL CSLLRGDGKC 4080 DNGTENRRKT AGRNMPARRS DNLTQERELR RPQDTRAGRN QRGNRQHASL LEDPGPKTGV 4140 PGQPDTTGCF IHQQLHSSTG NMRQDRTPTE TIVLLDDDED DRAAPSR 4187 |
Gene Ontology | GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW. GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro. GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |