CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032503
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 T-complex protein 1 subunit alpha 
Protein Synonyms/Alias
  
Gene Name
 TGGT1_117890, TGME49_029990, TGVEG_025520 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
187ITERGDVKYPVSSINacetylation[1, 2]
Reference
 [1] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907]
 [2] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Chaperone; Complete proteome; Cytoplasm; Nucleotide-binding; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 548 AA 
Protein Sequence
MALAIFGDRQ SGQDVRTANA AAVQSIANIL RSSLGPQGLD KMLVDDIGDM TITNDGATIL 60
KQLEVQHPAA KVLVELSDLQ DKEVGDGTTS VVLLAAEFLR VGNQLVKEGV HPTAVIAGFK 120
LAMKESVKFI QEHLTSRVDA NNREVLMNVA TTTISSKLIG TETAHFADLV VRAILSVKMI 180
TERGDVKYPV SSINIIKTHG KSMRESSLVE GYALKAGRAA QGMPQCVKNA KVALLDFNLR 240
QHRMQLGVQI QVDNPEELEK IRQKEKDITA AKIQKILASG ANVILTTQGI DDMAMKYFVE 300
AGAIAVRRVD RKDLRRIAKI TEGTVVLTMA TLDGDEKFDA SCLGTCEEVY EERIGDWDHL 360
MFKGCKGGKA ATVILRGANE YMLDEVDRSV HDALCAVSRA LEYTHVCPGG GAVETSLSVY 420
LENFARTLGS REQLAIAAFA EALLIIPKTL AVNAALDATE LVARLRAVHA KAQGQLLDAA 480
GNGDEELKWH GLDLTSGKTR NNMAAGVIEA AVSKTKALRF ATEAAVTILR IDDLIKIAPE 540
PERGQQDD 548 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
 GO:0006457; P:protein folding; IEA:InterPro. 
Interpro
 IPR012715; Chap_CCT_alpha.
 IPR017998; Chaperone_TCP-1.
 IPR002194; Chaperonin_TCP-1_CS.
 IPR002423; Cpn60/TCP-1.
 IPR027409; GroEL-like_apical_dom.
 IPR027413; GROEL-like_equatorial.
 IPR027410; TCP-1-like_intermed. 
Pfam
 PF00118; Cpn60_TCP1 
SMART
  
PROSITE
 PS00750; TCP1_1
 PS00751; TCP1_2
 PS00995; TCP1_3 
PRINTS
 PR00304; TCOMPLEXTCP1.