CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043584
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 F-box only protein 22 
Protein Synonyms/Alias
  
Gene Name
 FBXO22 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
90IQPFHFIKDPKNLTLacetylation[1, 2]
93FHFIKDPKNLTLERHubiquitination[3]
Reference
 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 160 AA 
Protein Sequence
MADSETFISL EECRGHKRAR KRTSMETALA LEKLFPKQCQ VLGIVTPGIV VTPMGSGSNR 60
PQEIEIGESG FALLFPQIEG IKIQPFHFIK DPKNLTLERH QLTEVGLLDN PELRVVLVFG 120
YNCCKVGASN YLQQVVSTFS DMNIILAGGQ VDNLSSLTSE 160 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0009267; P:cellular response to starvation; IEA:Compara.
 GO:0006913; P:nucleocytoplasmic transport; IEA:Compara.
 GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Compara.
 GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IEA:Compara.
 GO:0000209; P:protein polyubiquitination; IEA:Compara.
 GO:0010830; P:regulation of myotube differentiation; IEA:Compara. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS