CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030879
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A 
Protein Synonyms/Alias
 cDNA FLJ54784, highly similar to Ankyrin repeat domain-containing protein 28 
Gene Name
 ANKRD28 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
115ANINAFDKKDRRAIHacetylation[1]
334GFSDCCRKLLSSGFDubiquitination[2]
655ALLQHGAKCLLRDSRubiquitination[2]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 ANK repeat; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 722 AA 
Protein Sequence
MLTFRTMKSE PHCTPQLTLE MQKSLNFLFY LEAVQVLLKH SADVNARDKN WQTPLHIAAA 60
NKAVKCAEAL VPLLSNVNVS DRAGRTALHH AAFSGHGEMV KLLLSRGANI NAFDKKDRRA 120
IHWAAYMGHI EVVKLLVSHG AEVTCKDKKS YTPLHAAASS GMISVVKYLL DLGVDMNEPN 180
AYGNTPLHVA CYNGQDVVVN ELIDCGAIVN QKNEKGFTPL HFAAASTHGA LCLELLVGNG 240
ADVNMKSKDG KTPLHMTALH GRFSRSQTII QSGAVIDCED KNGNTPLHIA ARYGHELLIN 300
TLITSGADTA KRGIHGMFPL HLAALSGFSD CCRKLLSSGF DIDTPDDFGR TCLHAAAAGG 360
NLECLNLLLN TGADFNKKDK FGRSPLHYAA ANCNYQCLFA LVGSGASVND LDERGCTPLH 420
YAATSDTDGK CLEYLLRNDA NPGIRDKQGY NAVHYSAAYG HRLCLQLIAS ETPLDVLMET 480
SGTDMLSDSD NRATISPLHL AAYHGHHQAL EVLVQSLLDL DVRNSSGRTP LDLAAFKGHV 540
ECVDVLINQG ASILVKDYIL KRTPIHAAAT NGHSECLRLL IGNAEPQNAV DIQDGNGQTP 600
LMLSVLNGHT DCVYSLLNKG ANVDAKDKWG RTALHRGAVT GHEECVDALL QHGAKCLLRD 660
SRGRTPIHLS AACGHIGVLG ALLQSAASMD ANPATADNHG YTALHWACYN ELLSMQPPSQ 720
TM 722 
Gene Ontology
  
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom. 
Pfam
 PF00023; Ank
 PF12796; Ank_2 
SMART
 SM00248; ANK 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT 
PRINTS
 PR01415; ANKYRIN.