CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034342
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 CAP-Gly domain-containing linker protein 1 
Protein Synonyms/Alias
  
Gene Name
 Clip1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
14SGLKAPTKILKPGSTacetylation[1]
35AAAAPVEKTIPSEKAacetylation[2]
758TSQLSAVKEKLLDLDubiquitination[3]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1426 AA 
Protein Sequence
MSMLKPSGLK APTKILKPGS TALKTPAAAA APVEKTIPSE KASGPPSSET QEEFVDDFRV 60
GERVWVNGNK PGFIQFLGET QFAPGQWAGI VLDEPIGKND GSVAGVRYFQ CEPLKGIFTR 120
PSKLTRKVQA EDEANGLQAA PGRTASPLST AAATMVSSSP ATPSNIPHKP SQSTAKEPSA 180
TPQISNLTKT ASESISNLSE AGSVKKGERE LKVGDRVLVG GTKAGVVRFL GETDFAKGEW 240
CGVELDEPLG KNDGAVAGTR YFQCQPKYGL FAPVHKVTKI GFPSTTPAKA KAAAVRRVMA 300
ATPASLKRSP SASSLSSMSS VASSVSSKPS RTGLLTETSS RYARKISGTT ALQEALKEKQ 360
QHIEQLLAER DLERAEVAKA TSHVGEIEQE LALARDGHDQ HVLELEAKMD QLRTMVEAAD 420
REKVELLNQL EEEKRKVEDL QFRVEEESIT KGDLETQTKL EHARTKELEQ SLLFEKTKAD 480
KLQRELEDTR VATVSEKSRI MELEKDLALR AQEVAELRRR LESSKPPGDV DMSLSLLQEI 540
SALQEKLEAI HTDHQGEMTS LKEHFGAREE AFQKEIKALH TATEKLSKEN ESLRSKLDHA 600
NKENSDVIAL WKSKLETAIA SHQQAMEELK VSFSKGIGTD SAEFAELKTQ IERLRLDYQH 660
EIESLQSKQD SERSAHAKEM ETMQAKLMKI IKEKEDSLEA VKARLDSAED QHLVEMEDTL 720
NKLQEAEIKV KELEVLQAKY TEQSEVIGNF TSQLSAVKEK LLDLDALRKA NSEGKLELET 780
LRQQLEGAEK QIKNLETERN AESSKANSIT KELQEKELVL TGLQDSLNQV NQVKETLEKE 840
LQTLKEKFAS TSEEAVSAQT RMQDTVNKLH QKEEQFNVLS SELEKLRENL TDMEAKFKEK 900
DDREDQLVKA KEKLENDIAE IMKMSGDNSS QLTKMNDELR LKERSVEELQ LKLTKANENA 960
SFLQKSIGEV TLKAEQSQQQ AARKHEEEKK ELEEKLLELE KKMETSYNQC QDLKAKYEKA 1020
SSETKTKHEE ILQNLQKMLA DTEDKLKAAQ EANRDLMQDM EELKTQADKA KAAQTAEDAM 1080
QIMEQMTKEK TETLASLEDT KQTNARLQNE LDTLKENNLK TVEELNKSKE LLSVENQKME 1140
EFKKEIETLK QAAAQKSQQL SALQEENVKL AEELGRTRDE VTSHQKLEEE RSVLNNQLLE 1200
MKKRESEFRK DADEEKASLQ KSISLTSALL TEKDAELEKL RNEVTVLRGE NATAKSLHSV 1260
VQTLESDKVK LELKVKNLEL QLKENKRQLS SSSGNTDAQA EEDERAQESQ IDFLNSVIVD 1320
LQRKNQDLKM KVEMMSEAAL NGNGEDLNSY DSDDQEKQSK KKPRLFCDIC DCFDLHDTED 1380
CPTQAQMSED PPHSTHHGSR SEERPYCEIC EMFGHWATNC NDDETF 1426 
Gene Ontology
 GO:0005881; C:cytoplasmic microtubule; IDA:MGI.
 GO:0035371; C:microtubule plus end; IDA:MGI.
 GO:0008017; F:microtubule binding; IDA:MGI.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR000938; CAP-Gly_domain.
 IPR001878; Znf_CCHC. 
Pfam
 PF01302; CAP_GLY 
SMART
 SM01052; CAP_GLY
 SM00343; ZnF_C2HC 
PROSITE
 PS00845; CAP_GLY_1
 PS50245; CAP_GLY_2 
PRINTS