Tag | Content |
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CPLM ID | CPLM-001415 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Putative hydrolase RBBP9 |
Protein Synonyms/Alias | B5T-overexpressed gene protein; Protein BOG; Retinoblastoma-binding protein 9; RBBP-9 |
Gene Name | Rbbp9 |
Gene Synonyms/Alias | Bog |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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124 | PWQWEKIKANCPHIV | acetylation | [1] |
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Reference | [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways. Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y. Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [ PMID: 22826441] |
Functional Description | May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1 (By similarity). |
Sequence Annotation | REGION 56 70 Retinoblastoma protein binding ACT_SITE 75 75 Charge relay system (Potential). ACT_SITE 138 138 Charge relay system (Potential). ACT_SITE 165 165 Charge relay system (Potential). MOD_RES 49 49 Phosphothreonine; by CK2 (Potential). MOD_RES 135 135 Phosphoserine; by CK2 (Potential). |
Keyword | Complete proteome; Cytoplasm; Direct protein sequencing; Hydrolase; Nucleus; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 186 AA |
Protein Sequence | MASPNKAVIV PGNGGGDVAT HGWYGWVKKG LEQIPGFQCL AKNMPDPITA RESIWLPFME 60 TELHCDEKTI IIGHSSGAIA AMRYAETHQV YALVLVSAYT SDLGDENERA SGYFSRPWQW 120 EKIKANCPHI VQFGSTDDPF LPWKEQQEVA DRLDAKLYKF TDRGHFQNTE FHELISVVKS 180 MLKGPE 186 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. GO:0042127; P:regulation of cell proliferation; IEA:Compara. |
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