CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039393
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Mitochondrial-processing peptidase subunit alpha 
Protein Synonyms/Alias
  
Gene Name
 Pmpca 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
102SGSRYEAKYLSGIAHacetylation[1]
470CTLIRNVKPEDIKRVacetylation[1]
475NVKPEDIKRVASKMLacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 522 AA 
Protein Sequence
MATAVWAAAR LLRGSAALCA RPKFGSPAHR RFSSGATYPN IPLSSPLPGV PKPIFATVDG 60
QEKFETKVTT LDNGLRVASQ NKFGQFCTLG ILINSGSRYE AKYLSGIAHF LEKLAFSSTA 120
RFDSKDEILL TLEKHGGICD CQTSRDTTMY AVSADSKGLD TVVGLLADVV LHPRLTDEEI 180
EMTRMAVQFE LEDLNMRPDP EPLLTEMIHE AAFRENTVGL HRFCPVENIG KIDREVLHSY 240
LKNYYTPDRM VLAGVGVEHE HLVECARKYL LGVQPAWGAP GAWMLTAQWH STRGGSSRWR 300
ETCQMSALAP PRFQSSHIGG ARELLLPEED FIPFAVLNMM MGGGGSFSAG GPGKGMFSRL 360
YLNVLNRHHW MYNATSYHHS YEDTGLLCIH ASADPRQVRE MVEIITKEFI LMGRTVDLVE 420
LERAKTQLMS MLMMNLESRP VIFEDVGRQV LATHSRKLPH ELCTLIRNVK PEDIKRVASK 480
MLRGKPAVAA LGDLTDLPTY EHIQAALSSR DGRLPRTYRL FR 522 
Gene Ontology
 GO:0046872; F:metal ion binding; IEA:InterPro.
 GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR011249; Metalloenz_LuxS/M16.
 IPR011237; Pept_M16_dom.
 IPR011765; Pept_M16_N.
 IPR001431; Pept_M16_Zn_BS.
 IPR007863; Peptidase_M16_C. 
Pfam
 PF00675; Peptidase_M16
 PF05193; Peptidase_M16_C 
SMART
  
PROSITE
 PS00143; INSULINASE 
PRINTS