UniProt Accession

 A1L130_RAT; A1L130; F1LLY0 

Genbank Protein ID

 AABR06033517; BC127511; CH473964 

Genbank Nucleotide ID

 AAI27512.1; EDM01885.1 

Protein Name

 Inhibitor of growth family, member 4 

Protein Synonyms/Alias

 Inhibitor of growth family, member 4, isoform CRA_c; Protein Ing4 

Gene Name

 Ing4 

Gene Synonyms/Alias

 rCG_29756 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
112	ARFEADLKEKQIESS	acetylation	[1]
114	FEADLKEKQIESSDY	acetylation	[1]
127	DYDSSSSKGRTQKEK	acetylation	[1]
142	KAARARSKGKNSDEE	acetylation	[1]
144	ARARSKGKNSDEEAP	acetylation	[1]
152	NSDEEAPKAAQKKLK	acetylation	[1]
232	LTTKPRGKWFCPRCS	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 245 AA 

Protein Sequence

Gene Ontology

 GO:0000123; C:histone acetyltransferase complex; IEA:Compara.
 GO:0003713; F:transcription coactivator activity; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006915; P:apoptotic process; IEA:Compara.
 GO:0007050; P:cell cycle arrest; IEA:Compara.
 GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IEA:Compara.
 GO:0006260; P:DNA replication; IEA:Compara.
 GO:0043966; P:histone H3 acetylation; IEA:Compara.
 GO:0043983; P:histone H4-K12 acetylation; IEA:Compara.
 GO:0043981; P:histone H4-K5 acetylation; IEA:Compara.
 GO:0043982; P:histone H4-K8 acetylation; IEA:Compara.
 GO:0008285; P:negative regulation of cell proliferation; IEA:Compara.
 GO:0045926; P:negative regulation of growth; IEA:Compara.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:Compara.
 GO:0043065; P:positive regulation of apoptotic process; IEA:Compara. 

Interpro

 IPR024610; ING_N.
 IPR019786; Zinc_finger_PHD-type_CS.
 IPR011011; Znf_FYVE_PHD.
 IPR001965; Znf_PHD.
 IPR019787; Znf_PHD-finger.
 IPR013083; Znf_RING/FYVE/PHD. 

Pfam

 PF12998; ING
 PF00628; PHD 

SMART

 SM00249; PHD 

PROSITE

 PS01359; ZF_PHD_1
 PS50016; ZF_PHD_2 

PRINTS