| Tag | Content |
|---|
| CPLM ID | CPLM-016022 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Putative tyrosine-protein phosphatase auxilin |
Protein Synonyms/Alias | DnaJ homolog subfamily C member 6 |
Gene Name | Dnajc6 |
Gene Synonyms/Alias | Kiaa0473 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 93 | GRLFSNLKDNLKDTL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles (By similarity). |
Sequence Annotation | REPEAT 61 64 1.
REPEAT 65 68 2.
REPEAT 69 72 3.
DOMAIN 80 247 Phosphatase tensin-type.
DOMAIN 253 391 C2 tensin-type.
DOMAIN 874 938 J.
REGION 61 72 3 X 4 AA approximate tandem repeats.
MOTIF 434 442 SH3-binding (Potential).
ACT_SITE 189 189 Phosphocysteine intermediate (Potential).
MOD_RES 595 595 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Chaperone; Complete proteome; Hydrolase; Phosphoprotein; Protein phosphatase; Reference proteome; Repeat; SH3-binding. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 938 AA |
Protein Sequence | MSLLGSYRKK TSSDGYESLQ LVDSHGDSSA RGAAAGTQRA TAGAVRSPAR QPPHRASTTD 60
SSGASSPDME PSYGGGLFDM VKGGAGRLFS NLKDNLKDTL KDTSSRVIQS VSSYTKGDLD 120
FTYVTSRIIV MSFPVDSVDI GFRNQVDDIR SFLDSRHLDH YTVYNLSPKS YRTAKFHSRV 180
SECSWPIRQA PSLHNLFAVC RNMYNWLLQN PKNVCVVHCL DGRAASSILV GAMFIFCNLY 240
STPGPAVRLL YAKRPGIGLS PSHRRYLGYM CDLLADKPYR PHFKPLTIKA ITVSPVPFFN 300
KQRNGCRPYC DVLIGETKIY STCTDFERMK EYRVQDGKIF IPLNITVQGD VIVSMYHLRS 360
TIGSRLQAKV TNTQIFQLQF HSGFIPLDTT VLKFTKPELD ACDVPEKYPQ LFQVTLDIEV 420
QPQDKVIDLT PPWEHYCTKD VNPSILFSSQ QEHQDTLALG GQAPADLPPD HPRNLGQGGF 480
FASLCWQDQK SEKSRCEEDH AALVNQESEQ SDDELLTLSS PHGNAEGDKP HGAKKPGKKQ 540
QEPAAPPPPE EVDLLGLEGS DVSTNFSSLA APPSNSELLS DLFGGVGATG PAQAGQAGVE 600
DVFHPSGPVS AQSTPRRTAT SASASPTLRV GEGATFDPFG APAKPPGQDL LGSFLNTSSA 660
SSDPFLQPTR SPSPTVHASS TPAVNIQPDI AGGWDWHTKP GGFGMGSKSA ATSPTGSSHG 720
TPTHQSKPQT LDPFADLGTL GSSSFASKPT TPTGLGGGFP PLSSPQKASP QPMGGGWQQP 780
AGYNWQQTQS KPQSSMPHSS PQNRPNYNVS FSAMPAGQSE RGKGSTNLEG KQKAADFEDL 840
LSSQGFNAHK DKKGPRTIAE MRKEEMAKEM DPEKLKILEW IEGKERNIRA LLSTMHTVLW 900
AGETKWKPVG MADLVTPEQV KKVYRRAVLV VHPDKATGQP YEQYAKMIFM ELNDAWSEFE 960
NQGQKPLY 968 |
Gene Ontology | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. GO:0035335; P:peptidyl-tyrosine dephosphorylation; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |