UniProt Accession

 SYUB_RAT; Q63754; Q5PPN9 

Genbank Protein ID

 D17764; BC087579 

Genbank Nucleotide ID

 BAA04610.1; AAH87579.1 

Protein Name

 Beta-synuclein 

Protein Synonyms/Alias

 Phosphoneuroprotein 14; PNP 14 

Gene Name

 Sncb 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
6	**MDVFMKGLSMAKE	acetylation	[1]
45	LYVGSKTKEGVVQGV	acetylation	[1]
58	GVASVAEKTKEQASH	acetylation	[1]
58	GVASVAEKTKEQASH	ubiquitination	[2]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 

Functional Description

 May be involved in neuronal plasticity. 

Sequence Annotation

 REPEAT 20 30 1.
 REPEAT 31 41 2.
 REPEAT 42 56 3; approximate.
 REPEAT 57 67 4.
 REGION 20 67 4 X 11 AA tandem repeats of [EGS]-K-T-K-
 MOD_RES 118 118 Phosphoserine; by BARK1, CK2 and GRK5 (By  

Keyword

 Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 137 AA 

Protein Sequence

Gene Ontology

 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0030426; C:growth cone; IDA:RGD.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0043025; C:neuronal cell body; IDA:RGD.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0043195; C:terminal bouton; IDA:RGD.
 GO:0043014; F:alpha-tubulin binding; IDA:RGD.
 GO:0048487; F:beta-tubulin binding; IDA:RGD.
 GO:0005509; F:calcium ion binding; IEA:Compara.
 GO:0042417; P:dopamine metabolic process; IEA:Compara.
 GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Compara.
 GO:0050808; P:synapse organization; IEA:Compara.
 GO:0007268; P:synaptic transmission; IEA:Compara. 

Interpro

 IPR001058; Synuclein.
 IPR002461; Synuclein_beta. 

Pfam

 PF01387; Synuclein 

SMART

  

PROSITE

  

PRINTS

 PR01213; BSYNUCLEIN.
 PR01211; SYNUCLEIN.