UniProt Accession

 CAPZB_YEAST; P13517; D6VVP8; Q07082 

Genbank Protein ID

 X62630; Z46861; M17223; BK006942 

Genbank Nucleotide ID

 CAA44497.1; CAA86917.1; AAA66935.1; DAA08514.1 

Protein Name

 F-actin-capping protein subunit beta 

Protein Synonyms/Alias

  

Gene Name

 CAP2 

Gene Synonyms/Alias

 YIL034C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
274	SSAEEANKDAQAEVI	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. 

Sequence Annotation

 MOD_RES 85 85 Phosphoserine.
 MOD_RES 92 92 Phosphoserine.  

Keyword

 Actin capping; Actin-binding; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 287 AA 

Protein Sequence

Gene Ontology

 GO:0030479; C:actin cortical patch; IDA:SGD.
 GO:0005884; C:actin filament; IPI:SGD.
 GO:0005934; C:cellular bud tip; IDA:SGD.
 GO:0008290; C:F-actin capping protein complex; IMP:SGD.
 GO:0043332; C:mating projection tip; IDA:SGD.
 GO:0005886; C:plasma membrane; IDA:SGD.
 GO:0071203; C:WASH complex; IEA:InterPro.
 GO:0051015; F:actin filament binding; ISS:SGD.
 GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
 GO:0051016; P:barbed-end actin filament capping; IDA:SGD.
 GO:0030447; P:filamentous growth; IMP:SGD. 

Interpro

 IPR019771; F-actin_capping_bsu_CS.
 IPR001698; WASH_F-actin_cap_beta. 

Pfam

 PF01115; F_actin_cap_B 

SMART

  

PROSITE

 PS00231; F_ACTIN_CAPPING_BETA 

PRINTS

 PR00192; FACTINCAPB.