CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037023
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Exportin-7 
Protein Synonyms/Alias
  
Gene Name
 XPO7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
33TTRLQAEKALVEFTNubiquitination[1]
70LAATCLTKLVSRTNNubiquitination[1, 2, 3]
1054IERNLLTKNRDRFTQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1088 AA 
Protein Sequence
MRDPGRKSLA QLENLCKQLY ETTDTTTRLQ AEKALVEFTN SPDCLSKCQL LLERGSSSYS 60
QLLAATCLTK LVSRTNNPLP LEQRIDIRNY VLNYLATRPK LATFVTQALI QLYARITKLG 120
WFDCQKDDYV FRNAITDVTR FLQDSVEYCI IGVTILSQLT NEINQADTTH PLTKHRKIAS 180
SFRDSSLFDI FTLSCNLLKQ ASGKNLNLND ESQHGLLMQL LKLTHNCLNF DFIGTSTDES 240
SDDLCTVQIP TSWRSAFLDS STLQLFFDLY HSIPPSFSPL VLSCLVQIAS VRRSLFNNAE 300
RAKFLSHLVD GVKRILENPQ SLSDPNNYHE FCRLLARLKS NYQLGELVKV ENYPEVIRLI 360
ANFTVTSLQH WEFAPNSVHY LLSLWQRLAA SVPYVKATEP HMLETYTPEV TKAYITSRLE 420
SVHIILRDGL EDPLEDTGLV QQQLDQLSTI GRCEYEKTCA LLVQLFDQSA QSYQELLQSA 480
SASPMDIAVQ EGRLTWLVYI IGAVIGGRVS FASTDEQDAM DGELVCRVLQ LMNLTDSRLA 540
QAGNEKLELA MLSFFEQFRK IYIGDQVQKS SKLYRRLSEV LGLNDETMVL SVFIGKIITN 600
LKYWGRCEPI TSKTLQLLND LSIGYSSVRK LVKLSAVQFM LNNHTSEHFS FLGINNQSNL 660
TDMRCRTTFY TALGRLLMVD LGEDEDQYEQ FMLPLTAAFE AVAQMFSTNS FNEQEAKRTL 720
VGLVRDLRGI AFAFNAKTSF MMLFEWIYPS YMPILQRAIE LWYHDPACTT PVLKLMAELV 780
HNRSQRLQFD VSSPNGILLF RETSKMITMY GNRILTLGEV PKDQVYALKL KGISICFSML 840
KAALSGSYVN FGVFRLYGDD ALDNALQTFI KLLLSIPHSD LLDYPKLSQS YYSLLEVLTQ 900
DHMNFIASLE PHVIMYILSS ISEGLTALDT MVCTGCCSCL DHIVTYLFKQ LSRSTKKRTT 960
PLNQESDRFL HIMQQHPEMI QQMLSTVLNI IIFEDCRNQW SMSRPLLGLI LLNEKYFSDL 1020
RNSIVNSQPP EKQQAMHLCF ENLMEGIERN LLTKNRDRFT QNLSAFRREV NDSMKNSTYG 1080
VNSNDMMS 1088 
Gene Ontology
 GO:0005643; C:nuclear pore; IEA:InterPro.
 GO:0008565; F:protein transporter activity; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; IEA:InterPro. 
Interpro
 IPR016024; ARM-type_fold.
 IPR001494; Importin-beta_N. 
Pfam
 PF03810; IBN_N 
SMART
 SM00913; IBN_N 
PROSITE
 PS50166; IMPORTIN_B_NT 
PRINTS