UniProt Accession

 Q8WX68_HUMAN; Q8WX68 

Genbank Protein ID

 AL137070 

Genbank Nucleotide ID

 CAD13299.1 

Protein Name

 BA251O17.4 (Similar to methylenetetrahydrofolate dehydrogenase(NADP+ dependent),methenyltetrahydrofolate cyclohydrolase,formyltetrahydrofolate synthetase (MTHFD1)) 

Protein Synonyms/Alias

  

Gene Name

 bA251O17.4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
58	SLSHQPDKKGVPRDF	acetylation	[1]

Reference

 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 

Functional Description

  

Sequence Annotation

  

Keyword

 Hydrolase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 101 AA 

Protein Sequence

Gene Ontology

 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:InterPro.
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
 GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro. 

Interpro

 IPR000559; Formate_THF_ligase.
 IPR027417; P-loop_NTPase. 

Pfam

 PF01268; FTHFS 

SMART

  

PROSITE

  

PRINTS