| Tag | Content |
|---|
| CPLM ID | CPLM-022694 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Plexin-C1 |
Protein Synonyms/Alias | Virus-encoded semaphorin protein receptor; CD232 |
Gene Name | Plxnc1 |
Gene Synonyms/Alias | Vespr |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 1404 | LDAQAENKKITDPDV | ubiquitination | [1] | | 1439 | PQFVFDIKKTPHIDS | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Receptor for SEMA7A, for vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8 (By similarity). |
Sequence Annotation | DOMAIN 35 452 Sema.
MOD_RES 984 984 Phosphoserine.
CARBOHYD 86 86 N-linked (GlcNAc...) (Potential).
CARBOHYD 143 143 N-linked (GlcNAc...) (Potential).
CARBOHYD 149 149 N-linked (GlcNAc...) (Potential).
CARBOHYD 252 252 N-linked (GlcNAc...) (Potential).
CARBOHYD 386 386 N-linked (GlcNAc...) (Potential).
CARBOHYD 407 407 N-linked (GlcNAc...) (Potential).
CARBOHYD 694 694 N-linked (GlcNAc...) (Potential).
CARBOHYD 773 773 N-linked (GlcNAc...) (Potential).
CARBOHYD 802 802 N-linked (GlcNAc...) (Potential).
DISULFID 64 87 By similarity.
DISULFID 156 194 By similarity.
DISULFID 283 329 By similarity.
DISULFID 455 472 By similarity.
DISULFID 461 506 By similarity.
DISULFID 464 481 By similarity.
DISULFID 475 487 By similarity. |
Keyword | Complete proteome; Disulfide bond; Glycoprotein; Membrane; Phosphoprotein; Receptor; Reference proteome; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1574 AA |
Protein Sequence | MEVSRRKTPP RPPYPAAPLP LIAYLLALAA PARGADEPVW RSEQAIGAIA ASRADGVFVA 60
SGSCLDQLDY SLKNRLSRLY RDQAGNCTEP VSLAPPARPR PGSSFSKLLL PYREGATGLE 120
GLLLTGWTFD RGACEVRPLG NLNRSSLRNG TEVVSCHPQG STAGVVYRAS GTDLWYLAVA 180
ATYVLPEPET ANRCNPAASD RDTAIALKNT EGRSLATQEL GRLKLRGSAG SLHFVDAFLW 240
NGSVYFPYYP YNYTSGAATG WPSMARIAQS TEVLFQGQAA LDCDHGHPEG RRLLLSSSLV 300
EAVDIWAGVF SAATGEGQER RSPATTALCL FRMSEIQAHA RSCSWDFQAT EHNCKEGDRP 360
ERVQPIASST LIHSDLTSVY GTVVMNRTVL FLGTGDGQLL KVVLGENLTS NCPEVIYEIK 420
EETPVFYKLV PHPMKNIYIY LTAGKEVRRI PVANCSKRKS CSECLAAADP HCGWCLPLQR 480
CTFQGDCTHA GSFENWLDIS SGPKKCPKIQ ILRSLRERTT VTIVGSISAR HSECVVKNAD 540
TGKLLCQGRS QLNWTCACNI PSRPSYNVLV VNATFSFPSW NLSERFNFTN CASLKECPAC 600
IRSGCAWCKR DKKCIHPFTP CEPSDYERNQ ELCQVAVEKS PKDSGGGRVK ESKRNRTDGA 660
VQVFYIKAIE PQKISTLGKS NVIVTGANFT QASNITMILR GTSTCERDVI RVSHVLNDTH 720
MKFSLPSSRK EMKDVCIQFD GGTCSSAGAL SYIALPHCSL IVPATTWISG GQNITIMGRN 780
FDVIDNLIIS HELKGNANVN INVSEYCAAT FCRFLAPNLK SSKVRTNVAV KLRVQDTYLD 840
CGTLQYLEDP RFTGYRVESE IDTELEVKIQ KENDNFNISK DDIDITLFHG ENKQFNCSFE 900
NITRNQDLTT ILCKIKSIKN ANTIASSSKK VRVKLGNLEL YVEQESVPST WYFLIALPIL 960
LAIVIVVAVV VTRYKSKELS RKQSQQLELL ESELRKEIRD GFAELQMDKL DVVDSFGTVP 1020
FLDYKHFALR TFFPESGGFT HIFTEDMHNR DANDKNESLT ALDALICNKS FLVTVIHTLE 1080
KQKNFSVKDR CLFASFLTIA LQTKLVYLTS ILEVLTRDLM EQCSNMQPKL MLRRTESVVE 1140
KLLTNWMSVC LSGFLRETVG EPFYLLVTTL NQKINKGPVD VITCKALYTL NEDWLLWQVP 1200
EFNTVALNVV FEKIPENESA DVCRNISVNV LDCDTIGQAK EKVFQAFLSK NGSPYGLQLN 1260
EIGLELQVGT RQKELLDIDS SSVILEDGIT KLNTIGHYEI SNGSTIKVFK KIANFTSDVE 1320
YSDDHCHLIL PDSEAFQVVQ GKRHRGKHKF KVKEMYLTKL LSTKVAIHSV LEKLFRSIWS 1380
LPNSRAPFAI KYFFDFLDAQ AENKKITDPD VVHIWKTNSL PLRFWVNILK NPQFVFDIKK 1440
TPHIDSCLSV IAQAFMDAFS LTEQQLGKEA PTNKLLYAKD IPTYKEEVKS YYKAIRDLPP 1500
LSSLEMEEFL TQESKKHENE FNEEVALTEI YKYIVKYFDE ILNKLERERG LEEAQKQLLH 1560
VKVLFDEKKK CKWM 1574 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005622; C:intracellular; IEA:InterPro. GO:0004872; F:receptor activity; IEA:InterPro. GO:0007275; P:multicellular organismal development; IEA:InterPro. GO:0007165; P:signal transduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |