CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007437
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cell division control protein 1 
Protein Synonyms/Alias
  
Gene Name
 CDC1 
Gene Synonyms/Alias
 DSR1; ESP2; YDR182W; YD9395.16 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
446PLPTSISKSKSKKSLubiquitination[1]
451ISKSKSKKSLTHSKYacetylation[2]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] mChIP-KAT-MS, a method to map protein interactions and acetylation sites for lysine acetyltransferases.
 Mitchell L, Huard S, Cotrut M, Pourhanifeh-Lemeri R, Steunou AL, Hamza A, Lambert JP, Zhou H, Ning Z, Basu A, Côté J, Figeys DA, Baetz K.
 Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):E1641-50. [PMID: 23572591] 
Functional Description
 Probable metallophosphoesterase which may participate in recombinational repair of double -strand breaks. 
Sequence Annotation
 METAL 95 95 Divalent metal cation 1 (By similarity).
 METAL 144 144 Divalent metal cation 1 (By similarity).
 METAL 144 144 Divalent metal cation 2 (By similarity).
 METAL 183 183 Divalent metal cation 2 (By similarity).
 METAL 323 323 Divalent metal cation 1 (By similarity).  
Keyword
 Cell cycle; Cell division; Complete proteome; Hydrolase; Membrane; Metal-binding; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 491 AA 
Protein Sequence
MVYRNRSKSV LSTHSKKSDD KAHYKSRSKK KSKSRSKKRL RIYWRYISIV WILWLGLISY 60
YESVVVKRAM KKCQWSTWED WPEGAESHRV GLFADPQIMD EYSYPGRPQI VNYFTRVIVD 120
HYHRRNWKYV QYYLDPDSNF FLGDLFDGGR NWDDKQWIKE YTRFNQIFPK KPLRRTVMSL 180
PGNHDIGFGD TVVESSLQRF SSYFGETSSS LDAGNHTFVL LDTISLSDKT NPNVSRVPRQ 240
FLDNFAMGSH PLPRILLTHV PLWRDPEQQT CGQLRESKEP FPIQKGHQYQ TVIENDISQE 300
ILTKIQPEIL FSGDDHDHCQ ISHSYPFQGK TKNAQEITVK SCAMNMGISR PAIQLLSLYN 360
PSDLTMVNAG GEYASKTYQT ELCYMPDPYK AIRMYLWGLL FSAAFIAYMH FFPKSFNNRV 420
ATIMNRVFTR PDGNTSDLPL PTSISKSKSK KSLTHSKYAV NDTRSIKQFL VNAIVLFVSV 480
MPIFIYFYTV V 491 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IDA:SGD.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0030036; P:actin cytoskeleton organization; IMP:SGD.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0030026; P:cellular manganese ion homeostasis; IGI:SGD.
 GO:0016311; P:dephosphorylation; IMP:SGD.
 GO:0006281; P:DNA repair; IMP:SGD. 
Interpro
 IPR004843; Metallo_PEstase_dom. 
Pfam
 PF00149; Metallophos 
SMART
  
PROSITE
  
PRINTS