UniProt Accession

 B5MC02_HUMAN; B5MC02 

Genbank Protein ID

 AC002064; AC004969 

Genbank Nucleotide ID

  

Protein Name

 Metalloreductase STEAP2 

Protein Synonyms/Alias

  

Gene Name

 STEAP2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
26	PNGINGIKDARKVTV	ubiquitination	[1]
30	NGIKDARKVTVGVIG	ubiquitination	[1]
64	VIGSRNPKFASEFFP	ubiquitination	[1, 2, 3]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 403 AA 

Protein Sequence

Gene Ontology

 GO:0016491; F:oxidoreductase activity; IEA:InterPro. 

Interpro

 IPR013130; Fe3_Rdtase_TM_dom.
 IPR016040; NAD(P)-bd_dom.
 IPR004455; NADP_OxRdtase_F420. 

Pfam

 PF03807; F420_oxidored
 PF01794; Ferric_reduct 

SMART

  

PROSITE

  

PRINTS