CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039058
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 E3 ubiquitin-protein ligase TRIM23 
Protein Synonyms/Alias
  
Gene Name
 Trim23 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
8MAALAVNKPGAGVDSubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; GTP-binding; Metal-binding; Nucleotide-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 573 AA 
Protein Sequence
MAALAVNKPG AGVDSGRQGS RGTAVVKVLE CGVCEDVFSL QGDKVPRLLL CGHTVCHDCL 60
TRLPLHGRAI RCPFDRQVTD LGDSGVWGLK KNFALLELLE RLQNGHIGQY GAAEEALGIS 120
GESIIRCDED EAHVASVYCT VCATHLCSEC SQVTHSTKTL AKHRRVPLAD KPHEKTMCCQ 180
HQVHAIEFVC LEEACQTSPL MCCVCKEYGK HQGHKHSVLE PEANQIRASI LDMAHCIRTF 240
TEEISDYSRK LVGIVQHIEG GEQIVEDGIG MAHTEHVPGT AENARSCVRA YFSDLHETLC 300
RQEEMALSVV DAHVREKLIW LRQQQEDMTI LLSQVSTACL HCKTLQQDDC RVVLAKQEIT 360
RLLETLQKQQ QQFTEVADHI QLDASIPVTF TKDNRVHIGP KMEIRVVTLG LDGAGKTTIL 420
FKLKQDEFMQ PIPTIGFNVE TVEYKNLKFT IWDVGGKHKL RPLWKHYYLN TQAVVFVVDS 480
SHRDRISEAH SELAKLLTEK ELRDALLLIF ANKQDVAGAL SVEEITELLS LHKLCCGRSW 540
YIQGCDARSG MGLYEGLDWL SRQLVAAGVL DVA 573 
Gene Ontology
 GO:0000139; C:Golgi membrane; IEA:Compara.
 GO:0005765; C:lysosomal membrane; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0019003; F:GDP binding; IEA:Compara.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:Compara.
 GO:0004842; F:ubiquitin-protein ligase activity; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006184; P:GTP catabolic process; IEA:GOC.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 
Interpro
 IPR003649; Bbox_C.
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR024156; Small_GTPase_ARF.
 IPR006689; Small_GTPase_ARF/SAR.
 IPR000315; Znf_B-box.
 IPR007087; Znf_C2H2.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS. 
Pfam
 PF00025; Arf
 PF00643; zf-B_box 
SMART
 SM00177; ARF
 SM00502; BBC
 SM00336; BBOX
 SM00184; RING 
PROSITE
 PS51417; ARF
 PS50119; ZF_BBOX
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS
 PR00328; SAR1GTPBP.