[1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113]
Functional Description
Acts as an important p53/TP53-apoptotic effector. Regulates TNF-alpha-mediated apoptosis in a p53/TP53-dependent manner.
GO:0005634; C:nucleus; IEA:Compara. GO:0006917; P:induction of apoptosis; IEA:Compara. GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IEA:Compara. GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IEA:Compara.