UniProt Accession

 Q7Z350_HUMAN; Q7Z350 

Genbank Protein ID

 AL162420; BX538121 

Genbank Nucleotide ID

 CAD98027.1 

Protein Name

 Kelch-like protein 9 

Protein Synonyms/Alias

 Putative uncharacterized protein DKFZp686L0695 

Gene Name

 DKFZp686L0695 

Gene Synonyms/Alias

 KLHL9 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
103	YNLIEVDKYVNNFIL	ubiquitination	[1]
111	YVNNFILKNFPALLS	ubiquitination	[2]
124	LSTGEFLKLPFERLA	ubiquitination	[2, 3]
167	PRMDYAAKLMKNIRF	ubiquitination	[3]
247	RQQLVVSKELRMYDE	ubiquitination	[2, 4]
295	SNYDTKGKTAVDTVF	ubiquitination	[2]
310	RFDPRYNKWMQVASL	ubiquitination	[1]
320	QVASLNEKRTFFHLS	ubiquitination	[2, 4]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Kelch repeat; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 549 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR011705; BACK.
 IPR000210; BTB/POZ-like.
 IPR011333; BTB/POZ_fold.
 IPR013069; BTB_POZ.
 IPR015916; Gal_Oxidase_b-propeller.
 IPR017096; Kelch-like_gigaxonin.
 IPR006652; Kelch_1. 

Pfam

 PF07707; BACK
 PF00651; BTB
 PF01344; Kelch_1 

SMART

 SM00875; BACK
 SM00225; BTB
 SM00612; Kelch 

PROSITE

 PS50097; BTB 

PRINTS