CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027730
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 NRF1 protein 
Protein Synonyms/Alias
 Nuclear factor erythroid 2-related factor 1; Nuclear respiratory factor 1; Nuclear respiratory factor 1, isoform CRA_b 
Gene Name
 NRF1 
Gene Synonyms/Alias
 hCG_1811093 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
139VLCISPSKPNPVFKVubiquitination[1]
214AFIPEMLKYSTGRGKubiquitination[1, 2]
267QALRTIVKNCYKQHGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 522 AA 
Protein Sequence
MEEHGVTQTE HMATIEAHAV AQQVQQVHVA TYTEHSMLSA DEDSPSSPED TSYDDSDILN 60
STAADEVTAH LAAAGPVGMA AAAAVATGKK RKRPHVFESN PSIRKRQQTR LLRKLRATLD 120
EYTTRVGQQA IVLCISPSKP NPVFKVFGAA PLENVVRKYK SMILEDLESA LAEHAPAPQE 180
VNSELPPLTI DGIPVSVDKM TQAQLRAFIP EMLKYSTGRG KPGWGKESCK PIWWPEDIPW 240
ANVRSDVRTE EQKQRVSWTQ ALRTIVKNCY KQHGREDLLY AFEDQQTQTQ ATATHSIAHL 300
VPSQTVVQTF SNPDGTVSLI QVGTGATVAT LADASELPTT VTVAQVNYSA VADGEVEQNW 360
ATLQGGEMTI QTTQASEATQ AVASLAEAAV AASQEMQQGA TVTMALNSEA AAHAVATLAE 420
ATLQGGGQIV LSGETAAAVG ALTGVQDANG LFMADRAGRK WILTDKATGL VQIPVSMYQT 480
VVTSLAQGNG PVQVAMAPVT TRISDSAVTM DGQAVEVVTL EQ 522 
Gene Ontology
  
Interpro
 IPR019526; Nrf1_activation-bd.
 IPR019525; Nrf1_NLS/DNA-bd_dimer. 
Pfam
 PF10492; Nrf1_activ_bdg
 PF10491; Nrf1_DNA-bind 
SMART
  
PROSITE
  
PRINTS