CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029795
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Arginine-glutamic acid dipeptide (RE) repeats, isoform CRA_b 
Protein Synonyms/Alias
 Arginine-glutamic acid dipeptide repeats protein 
Gene Name
 RERE 
Gene Synonyms/Alias
 hCG_2008872 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
110ESGYDAGKALQRLVKubiquitination[1]
867SQSARFYKHLDRGYNubiquitination[1]
1056RELRERMKPGFEVKPubiquitination[1, 2, 3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1298 AA 
Protein Sequence
MDDPFSPCRR LNSTQGEIRV GPSHQAKLPD LQPFPSPDGD TVTQHEELVW MPGVNDCDLL 60
MYLRAARSMA AFAGMCDGGS TEDGCVAASR DDTTLNALNT LHESGYDAGK ALQRLVKKPV 120
PKLIEKCWTE DEVKRFVKGL RQYGKNFFRI RKELLPNKET GELITFYYYW KKTPEAASSR 180
AHRRHRRQAV FRRIKTRTAS TPVNTPSRPP SSEFLDLSSA SEDDFDSEDS EQELKGYACR 240
HCFTTTSKDW HHGGRENILL CTDCRIHFKK YGELPPIEKP VDPPPFMFKP VKEEDDGLSG 300
KHSMRTRRSR GSMSTLRSGR KKQPASPDGR TSPINEDIRS SGRNSPSAAS TSSNDSKAET 360
VKKSAKKVKE EASSPLKSNK RQREKVASDT EEADRTSSKK TKTQEISRPN SPSEGEGESS 420
DSRSVNDEGS SDPKDIDQDN RSTSPSIPSP QDNESDSDSS AQQQMLQAQP PALQAPTGVT 480
PAPSSAPPGT PQLPTPGPTP SATAVPPQGS PTASQAPNQP QAPTAPVPHT HIQQAPALHP 540
QRPPSPHPPP HPSPHPPLQP LTGSAGQPSA PSHAQPPLHG QGPPGPHSLQ AGPLLQHPGP 600
PQPFGLPPQA SQGQAPLGTS PAAAYPHTSL QLPASQSALQ SQQPPREQPL PPAPLAMPHI 660
KPPPTTPIPQ LPAPQAHKHP PHLSGPSPFS MNANLPPPPA LKPLSSLSTH HPPSAHPPPL 720
QLMPQSQPLP SSPAQPPGLT QSQNLPPPPA SHPPTGLHQV APQPPFAQHP FVPGGPPPIT 780
PPTCPSTSTP PAGPGTSAQP PCSGAAASGG SIAGGSSCPL PTVQIKEEAL DDAEEPESPP 840
PPPRSPSPEP TVVDTPSHAS QSARFYKHLD RGYNSCARTD LYFMPLAGSK LAKKREEAIE 900
KAKREAEQKA REEREREKEK EKERERERER EREAERAAKA SSSAHEGRLS DPQLSGPGHM 960
RPSFEPPPTT IAAVPPYIGP DTPALRTLSE YARPHVMSPT NRNHPFYMPL NPTDPLLAYH 1020
MPGLYNVDPT IRERELRERE IREREIRERE LRERMKPGFE VKPPELDPLH PAANPMEHFA 1080
RHSALTIPPT AGPHPFASFH PGLNPLERER LALAGPQLRP EMSYPDRLAA ERIHAERMAS 1140
LTSDPLARLQ MFNVTPHHHQ HSHIHSHLHL HQQDPLHQGS AGPVHPLVDP LTAGPHLARF 1200
PYPPGTLPNP LLGQPPHEHE MLRHPVFGTP YPRDLPGAIP PPMSAAHQLQ AMHAQSAELQ 1260
RLAMEQQWLH GHPHMHGGHL PSQEDYYSRL KKEGDKQL 1298 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0003682; F:chromatin binding; IEA:InterPro.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR002951; Atrophin-like.
 IPR000949; ELM2_dom.
 IPR009057; Homeodomain-like.
 IPR001005; SANT/Myb.
 IPR017884; SANT_dom.
 IPR000679; Znf_GATA. 
Pfam
 PF03154; Atrophin-1
 PF01448; ELM2
 PF00320; GATA 
SMART
 SM00717; SANT
 SM00401; ZnF_GATA 
PROSITE
 PS51156; ELM2
 PS51293; SANT 
PRINTS