| Tag | Content |
|---|
| CPLM ID | CPLM-022174 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | ATP-binding cassette sub-family B member 8, mitochondrial |
Protein Synonyms/Alias | Mitochondrial ATP-binding cassette 1; M-ABC1 |
Gene Name | ABCB8 |
Gene Synonyms/Alias | MABC1 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 230 | ITFFDANKTGQLVSR | ubiquitination | [1] | | 246 | TTDVQEFKSSFKLVI | ubiquitination | [1] | | 556 | MENIRFGKLEASDEE | ubiquitination | [1] | | 611 | AIARALIKQPTVLIL | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | |
Sequence Annotation | DOMAIN 148 437 ABC transmembrane type-1.
DOMAIN 472 709 ABC transporter.
NP_BIND 507 514 ATP (Potential). |
Keyword | Alternative splicing; ATP-binding; Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Nucleotide-binding; Polymorphism; Reference proteome; Transit peptide; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 735 AA |
Protein Sequence | MLVHLFRVGI RGGPFPGRLL PPLRFQTFSA VRYSDGYRSS SLLRAVAHLR SQLWAHLPRA 60
PLAPRWSPSA WCWVGGALLG PMVLSKHPHL CLVALCEAEE APPASSTPHV VGSRFNWKLF 120
WQFLHPHLLV LGVAVVLALG AALVNVQIPL LLGQLVEVVA KYTRDHVGSF MTESQNLSTH 180
LLILYGVQGL LTFGYLVLLS HVGERMAVDM RRALFSSLLR QDITFFDANK TGQLVSRLTT 240
DVQEFKSSFK LVISQGLRSC TQVAGCLVSL SMLSTRLTLL LMVATPALMG VGTLMGSGLR 300
KLSRQCQEQI ARAMGVADEA LGNVRTVRAF AMEQREEERY GAELEACRCR AEELGRGIAL 360
FQGLSNIAFN CMVLGTLFIG GSLVAGQQLT GGDLMSFLVA SQTVQRSMAN LSVLFGQVVR 420
GLSAGARVFE YMALNPCIPL SGGCCVPKEQ LRGSVTFQNV CFSYPCRPGF EVLKDFTLTL 480
PPGKIVALVG QSGGGKTTVA SLLERFYDPT AGVVMLDGRD LRTLDPSWLR GQVVGFISQE 540
PVLFGTTIME NIRFGKLEAS DEEVYTAARE ANAHEFITSF PEGYNTVVGE RGTTLSGGQK 600
QRLAIARALI KQPTVLILDE ATSALDAESE RVVQEALDRA SAGRTVLVIA HRLSTVRGAH 660
CIVVMADGRV WEAGTHEELL KKGGLYAELI RRQALDAPRT AAPPPKKPEG PRSHQHKS 718 |
Gene Ontology | GO:0043190; C:ATP-binding cassette (ABC) transporter complex; TAS:ProtInc. GO:0016021; C:integral to membrane; IBA:RefGenome. GO:0005740; C:mitochondrial envelope; TAS:ProtInc. GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. GO:0005730; C:nucleolus; IDA:HPA. GO:0005524; F:ATP binding; TAS:ProtInc. GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IBA:RefGenome. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |