CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014369
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Equilibrative nucleoside transporter 2 
Protein Synonyms/Alias
 36 kDa hydrophobic nucleolar protein; 36 kDa nucleolar protein HNP36; Delayed-early response protein 12; Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter; Equilibrative NBMPR-insensitive nucleoside transporter; Nucleoside transporter, ei-type; Solute carrier family 29 member 2 
Gene Name
 Slc29a2 
Gene Synonyms/Alias
 Der12; Ent2; Hnp36 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
237PTQELETKAELLQADubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Mediates equilibrative transport of purine and pyrimidine nucleosides, and the purine base hypoxanthine. 
Sequence Annotation
 MOD_RES 252 252 Phosphoserine (By similarity).
 CARBOHYD 56 56 N-linked (GlcNAc...) (Potential).  
Keyword
 Cell membrane; Complete proteome; Glycoprotein; Membrane; Nucleus; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 456 AA 
Protein Sequence
MARGNAPRDS YHLVGISFFI LGLGTLLPWN FFITAIPYFQ GRLAGTNSSA ETMGTNHTSP 60
TDTFNFNNWV TLLSQLPLLL FTLLNSFLYQ CIPESVRILG SLLAILLLFA LTAALVKVDL 120
SPGLFFSVTM ASVWFINSFC AVLQGSLFGQ LGTMPSTYST LFLSGQGLAG IFAALAMLMS 180
LASGVDAQTS ALGYFITPCV GILLSIVCYL SLPHLKFARY YLTEKLSQAP TQELETKAEL 240
LQADEKNGVP ISPQQASPTL DLDPEKEPEP EEPQKPGKPS VFVVFRKIWL TALCLVLVFT 300
VTLSVFPAIT AMVTTSSNSP GKWGLFFNPI CCFLLFNVMD WLGRSLTSYF LWPDEDSQQL 360
LPLLVCLRFL FVPLFMLCHV PQHARLPIIF RQDAYFITFM LLFAVSNGYL VSLTMCLAPR 420
QVLPHEREVA GALMTFFLAL GLSCGASLSF LFKALL 456 
Gene Ontology
 GO:0016323; C:basolateral plasma membrane; ISS:UniProtKB.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
 GO:0005337; F:nucleoside transmembrane transporter activity; IDA:MGI.
 GO:0015858; P:nucleoside transport; IDA:MGI. 
Interpro
 IPR002259; Eqnu_transpt.
 IPR016196; MFS_dom_general_subst_transpt. 
Pfam
 PF01733; Nucleoside_tran 
SMART
  
PROSITE
  
PRINTS
 PR01130; DERENTRNSPRT.