CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041730
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphorylase 
Protein Synonyms/Alias
  
Gene Name
 Pygm 
Gene Synonyms/Alias
 rCG_48197 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
10RPLSDQDKRKQISVRacetylation[1]
29VENVSDLKKNFNRHLacetylation[1]
78TQQHYYEKDPKRIYYacetylation[1]
192RYGNPWEKARPEFTLacetylation[1]
256APNDFNLKDFNVGGYacetylation[1]
333NFDAFPDKVAIQLNDacetylation[1]
438LVEEGAVKRINMAHLacetylation[1]
465RIHSEILKKTIFKDFacetylation[1]
470ILKKTIFKDFYELEPacetylation[1]
537AFIRDVAKVKQENKLacetylation[1]
545VKQENKLKFSAYLERacetylation[1]
555AYLEREYKVHINPNSacetylation[1]
569SLFDVQVKRIHEYKRacetylation[1]
793DKVSELYKNPREWTRacetylation[1]
811RNIATSGKFSSDRTIacetylation[1]
841RLPAPDEKI******acetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity). 
Sequence Annotation
  
Keyword
 Carbohydrate metabolism; Complete proteome; Glycosyltransferase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 842 AA 
Protein Sequence
MSRPLSDQDK RKQISVRGLA GVENVSDLKK NFNRHLHFTL VKDRNVATPR DYYFALAHTV 60
RDHLVGRWIR TQQHYYEKDP KRIYYLSLEF YMGRTLQNTM VNLALENACD EATYQLGLDM 120
EELEEIEEDA GLGNGGLGRL AACFLDSMAT LGLAAYGYGI RYEFGIFNQK ICGGWQMEEA 180
DDWLRYGNPW EKARPEFTLP VHFYGRVEHT SQGAKWVDTQ VVLAMPYDTP VPGYRNNVVN 240
TMRLWSAKAP NDFNLKDFNV GGYIQAVLDR NLAENISRVL YPNDNFFEGK ELRLKQEYFV 300
VAATLQDIIR RFKSSKFGCR DPVRTNFDAF PDKVAIQLND THPSLAIPEL MRILVDLERL 360
DWDKAWDVTV KTCAYTNHTV LPEALERWPV HLMETLLPRH LQIIYEINQR FLNRVAAAFP 420
GDVDRLRRMS LVEEGAVKRI NMAHLCIAGS HAVNGVARIH SEILKKTIFK DFYELEPHKF 480
QNKTNGITPR RWLVLCNPGL AEVIAERIGE EYISDLDQLR KLLSYVDDEA FIRDVAKVKQ 540
ENKLKFSAYL EREYKVHINP NSLFDVQVKR IHEYKRQLLN CLHIITLYNR IKREPNRFMV 600
PRTIMIGGKA APGYHMAKMI IKLITAIGDV VNHDPAVGDR LRVIFLENYR VSLAEKVIPA 660
ADLSEQISTA GTEASGTGNM KFMLNGALTI GTMDGANVEM AEEAGEDNFF IFGMRVEDVE 720
RLDQRGYNAQ EYYDRIPELR QIIEQLSSGF FSPKQPDLFK DIVNMLMHHD RFKVFADYEE 780
YIKCQDKVSE LYKNPREWTR MVIRNIATSG KFSSDRTIAQ YAREIWGVEP SRQRLPAPDE 840
KI 842 
Gene Ontology
 GO:0008184; F:glycogen phosphorylase activity; IEA:Compara.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0005980; P:glycogen catabolic process; IEA:Compara. 
Interpro
 IPR011833; Glycg_phsphrylas.
 IPR000811; Glyco_trans_35. 
Pfam
 PF00343; Phosphorylase 
SMART
  
PROSITE
 PS00102; PHOSPHORYLASE 
PRINTS