CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026696
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Isoprenyl transferase 
Protein Synonyms/Alias
  
Gene Name
 uppS 
Gene Synonyms/Alias
 RPA2918 
Created Date
 July 27, 2013 
Organism
 Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) 
NCBI Taxa ID
 258594 
Lysine Modification
Position
Peptide
Type
References
226IHWPDFDKAALEGAIacetylation[1]
Reference
 [1] System-wide studies of N-lysine acetylation in Rhodopseudomonas palustris reveal substrate specificity of protein acetyltransferases.
 Crosby HA, Pelletier DA, Hurst GB, Escalante-Semerena JC.
 J Biol Chem. 2012 May 4;287(19):15590-601. [PMID: 22416131
Functional Description
 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity). 
Sequence Annotation
 ACT_SITE 74 74 Proton acceptor (By similarity).
 METAL 26 26 Magnesium (By similarity).
 METAL 213 213 Magnesium (By similarity).
 BINDING 31 31 Substrate (By similarity).
 BINDING 39 39 Substrate (By similarity).
 BINDING 43 43 Substrate (By similarity).
 BINDING 75 75 Substrate (By similarity).
 BINDING 77 77 Substrate (By similarity).
 BINDING 194 194 Substrate (By similarity).  
Keyword
 Complete proteome; Magnesium; Metal-binding; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 252 AA 
Protein Sequence
MSKAAAPLPD PSDPPSAPAH VAIIMDGNGR WAAARGLPRA EGHRRGVEAL RRVVRASSEL 60
GIQYLTIFSF SSENWARPAT EIVDLFGLLR RFIRNDLASL HRDGVRIRVI GERDRLDRDL 120
CAMLDEAQEL TRNNTKLNLV VAFNYGSRQE IANAAQRLAR EVAEGKRDPA TIDIETLGRY 180
LDAPDIPDPD LIIRTSGEQR LSNFLMWQAA YSELVFVPIH WPDFDKAALE GAIAEYSRRE 240
RRFGGLAAKT GS 252 
Gene Ontology
 GO:0000287; F:magnesium ion binding; IEA:HAMAP.
 GO:0004659; F:prenyltransferase activity; IEA:HAMAP. 
Interpro
 IPR001441; UPP_synth-like.
 IPR018520; UPP_synth-like_CS. 
Pfam
 PF01255; Prenyltransf 
SMART
  
PROSITE
 PS01066; UPP_SYNTHASE 
PRINTS