CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025929
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mov10, Moloney leukemia virus 10, homolog (Mouse), isoform CRA_a 
Protein Synonyms/Alias
 Putative helicase MOV-10 
Gene Name
 MOV10 
Gene Synonyms/Alias
 hCG_38463 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
15ANLAYVTKTRVRFFRubiquitination[1, 2, 3, 4]
34ADVRFPEKRRMKLGSubiquitination[2]
38FPEKRRMKLGSDISKubiquitination[2, 3, 4]
53HHKSLLAKIFYDRAEubiquitination[1, 2, 3, 4, 5]
65RAEYLHGKHGVDVEVubiquitination[2, 4]
92IRLDLNRKEVLTLRLacetylation[4]
92IRLDLNRKEVLTLRLubiquitination[2]
195SPLAAQLKPMTPFKRubiquitination[2]
201LKPMTPFKRTRITGNubiquitination[2]
268PKEIAEIKAQLETALubiquitination[2]
283KWRNYEVKLRLLLHLubiquitination[2]
358QEDPITYKGFVHKVEubiquitination[5]
433PLLPSDVKLKLYDRSubiquitination[2, 3, 4, 5]
435LPSDVKLKLYDRSLEubiquitination[2]
474FGPPGTGKTVTLVEAubiquitination[2]
483VTLVEAIKQVVKHLPubiquitination[2]
491QVVKHLPKAHILACAubiquitination[2]
537RMVPEDIKPCCNWDAubiquitination[2]
546CCNWDAKKGEYVFPAubiquitination[2, 4]
639LRSPLTQKHGLGYSLubiquitination[2, 4, 5]
658LTYNSLYKKGPDGYDubiquitination[2]
659TYNSLYKKGPDGYDPubiquitination[2, 4]
671YDPQFITKLLRNYRSubiquitination[1, 2, 3, 4]
728IFHGVMGKDEREGNSubiquitination[2]
760LLLAPSSKKGKARLSubiquitination[4, 6]
761LLAPSSKKGKARLSPubiquitination[2]
790KIRYCITKLDRELRGubiquitination[2, 4]
802LRGLDDIKDLKVGSVubiquitination[2, 4, 5]
805LDDIKDLKVGSVEEFubiquitination[2]
911NLLQGLSKLSPSTSGubiquitination[2, 4, 5]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [5] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [6] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 947 AA 
Protein Sequence
MLYGMKIANL AYVTKTRVRF FRLDRWADVR FPEKRRMKLG SDISKHHKSL LAKIFYDRAE 60
YLHGKHGVDV EVQGPHEARD GQLLIRLDLN RKEVLTLRLR NGGTQSVTLT HLFPLCRTPQ 120
FAFYNEDQEL PCPLGPGECY ELHVHCKTSF VGYFPATVLW ELLGPGESGS EGAGTFYIAR 180
FLAAVAHSPL AAQLKPMTPF KRTRITGNPV VTNRIEEGER PDRAKGYDLE LSMALGTYYP 240
PPRLRQLLPM LLQGTSIFTA PKEIAEIKAQ LETALKWRNY EVKLRLLLHL EELQMEHDIR 300
HYDLESVPMT WDPVDQNPRL LTLEVPGVTE SRPSVLRGDH LFALLSSETH QEDPITYKGF 360
VHKVELDRVK LSFSMSLLSR FVDGLTFKVN FTFNRQPLRV QHRALELTGR WLLWPMLFPV 420
APRDVPLLPS DVKLKLYDRS LESNPEQLQA MRHIVTGTTR PAPYIIFGPP GTGKTVTLVE 480
AIKQVVKHLP KAHILACAPS NSGADLLCQR LRVHLPSSIY RLLAPSRDIR MVPEDIKPCC 540
NWDAKKGEYV FPAKKKLQEY RVLITTLITA GRLVSAQFPI DHFTHIFIDE AGHCMEPESL 600
VAIAGLMEVK ETGDPGGQLV LAGDPRQLGP VLRSPLTQKH GLGYSLLERL LTYNSLYKKG 660
PDGYDPQFIT KLLRNYRSHP TILDIPNQLY YEGELQACAD VVDRERFCRW AGLPRQGFPI 720
IFHGVMGKDE REGNSPSFFN PEEAATVTSY LKLLLAPSSK KGKARLSPRS VGVISPYRKQ 780
VEKIRYCITK LDRELRGLDD IKDLKVGSVE EFQGQERSVI LISTVRSSQS FVQLDLDFNL 840
GFLKNPKRFN VAVTRAKALL IIVGNPLLLG HDPDWKVFLE FCKENGGYTG CPFPAKLDLQ 900
QGQNLLQGLS KLSPSTSGPH SHDYLPQERE GEGGLSLQVE PEWRNEL 947 
Gene Ontology
  
Interpro
 IPR026122; MOV-10/Armitage.
 IPR027417; P-loop_NTPase. 
Pfam
  
SMART
  
PROSITE
  
PRINTS